Electroencephalographic and behavioral correlates in rats during repeated ethanol withdrawal syndromes

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Tolerance to, and dependence on, some non-opiate psychotropic drugs.

1971 • 761 citations

Induction of physical dependence upon ethanol and the associated behavioral changes in rats

1975 • 740 citations

Kindling as a Model for Alcohol Withdrawal Syndromes

1978 • 470 citations

Alcohol tolerance and dependence

1980 • 419 citations

Relationship of alcohol dose to intensity of withdrawal signs in mice.

1972 • 329 citations

Criteria for an animal model of alcoholism

1973 • 238 citations

Body temperature in mice: a quantitative measure of alcohol tolerance and physical dependence.

1976 • 228 citations

Alcohol Withdrawal Syndrome in Mice.

1969 • 222 citations

Effects of single doses and chronic administration of ethanol on experimental seizures in mice.

1958 • 177 citations

Behavioral Studies of Alcoholism

1972 • 157 citations

A Critique of Animal Analogues of Alcoholism

1979 • 149 citations

Acquisition and loss of tolerance to ethanol by the rat.

1969 • 148 citations

The Effects of Alcohol on the Central Nervous System in Humans

1972 • 146 citations

Alcohol withdrawal in mice: Electroencephalographic and behavioral correlates

1974 • 126 citations

Modifications in the response to alcohol following the establishment of physical dependence

1971 • 124 citations

THE REINFORCING PROPERTY OF ETHANOL IN THE RHESUS MONKEY: I. INITIATION, MAINTENANCE AND TERMINATION OF INTRAVENOUS ETHANOL‐REINFORCED RESPONDING*†

1973 • 118 citations

Microdetermination of alcohol in blood by gas–liquid chromatography

1968 • 111 citations

Ethanol dependence in the rat: A parametric analysis

1975 • 101 citations

Rates of onset and decay of alcohol physical dependence in mice.

1974 • 84 citations

The effects of chronic administration of ethanol on startle thresholds in rats

1971 • 77 citations

Alcohol withdrawal syndrome in rats: Neural and behavioral correlates

1973 • 74 citations

Impaired development of tolerance to morphine analgesia in rats with hereditary diabetes insipidus

1976 • 73 citations

Potentiation of ethanol withdrawal by prior dependence

1979 • 64 citations

Intensification of the alcohol withdrawal syndrome by repeated brain stimulation

1975 • 62 citations

Accelerated development of tolerance during repeated cycles of ethanol exposure

1978 • 61 citations

ELECTROENCEPHALOGRAPHIC CHANGES ASSOCIATED WITH CHRONIC ALCOHOLIC INTOXICATION AND THE ALCOHOL ABSTINENCE SYNDROME

1956 • 61 citations

Biochemical Mechanisms of Alcohol Addiction

1971 • 50 citations

Ethanol dependence in the rat: its production and characteristics.

1972 • 48 citations

The effect of chronic ethanol treatment on behaviour and central monoamines in the rat

1977 • 47 citations

Sleep during chronic ethanol administration and withdrawal in rats.

1978 • 46 citations

Biological aspects of alcoholism

1997 • 40 citations

The modification of the ethanol withdrawal syndrome in rats by Di-n-propylacetate

1976 • 38 citations

Changes in the neuro-excitability of alcohol-dependent rats undergoing withdrawal as measured by the pentylenetetrazole seizure threshold

1973 • 37 citations

Electrographic and behavioral effects of diazepam during alcohol withdrawal stage in cats

1970 • 34 citations

Drinking patterns as predictors of alcohol withdrawal reactions in DBA/2J mice.

1976 • 29 citations

Ethanol dependence in the rat: Role of non-specific and limbic regions in the withdrawal reaction

1978 • 27 citations

Electroencephalographic signs of ethanol tolerance and physical dependence in the cat

1975 • 26 citations

A rapid technique for producing ethanol dependence in the rat

1974 • 24 citations

Ethanol dependence in the rat: Temporal changes in neuroexcitability following withdrawal

1978 • 21 citations

Ethanol dependence in the rat: Role of extrapyramidal motor systems in the withdrawal reaction

1978 • 15 citations

Increased CNS sensitivity to flurothyl as a measure of physical dependence in mice following morphine, phenobarbital, and ethanol treatment

1976 • 14 citations

Subcutaneous silastic implants: Maintenance of high blood ethanol levels in rats drinking a liquid diet

1980 • 13 citations

The Neural Basis of Ethanol Dependence: is the Withdrawal Reaction Mediated by Localized Changes in Synaptic Excitability?

1980 • 8 citations

Alcohol Withdrawal Reactions in Rhesus Monkeys

1977 • 7 citations