The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

How the λ repressor and cro work

1980 • 452 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

The human β-interferon gene enhancer is under negative control

1986 • 395 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Synergistic activation and repression of transcription by Drosophila homeobox proteins

1989 • 353 citations

Stable transcription complexes of Xenopus 5S RNA genes: A means to maintain the differentiated state

1982 • 352 citations

Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus

1984 • 341 citations

Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.

1987 • 327 citations

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region.

1987 • 294 citations

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator

1987 • 278 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome.

1989 • 195 citations

MULTIPARTITE GENETIC CONTROL ELEMENTS: COMMUNICATION BY DNA LOOP

1989 • 188 citations

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

1989 • 184 citations

E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.

1989 • 182 citations

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

1989 • 176 citations

A bacteriophage RNA polymerase transcribes through a Xenopus 5S RNA gene transcription complex without disrupting it

1986 • 169 citations

Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters.

1979 • 147 citations

SV40 T antigen binding site mutations that affect autoregulation

1983 • 145 citations

Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs

1989 • 130 citations

In vitro formation of short RNA polymerase II transcripts that terminate within the HIV-1 and HIV-2 promoter-proximal downstream regions.

1989 • 130 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

Dual promoter control of the escherichia coli lactose operon

1984 • 124 citations

The specific DNA recognition sequence of the bovine papillomavirus E2 protein is an E2-dependent enhancer.

1988 • 124 citations

Lac repressor is a transient gene-activating protein

1987 • 123 citations

Homeo Domain of the Yeast Repressor α2 Is a Sequence-Specific DNA-Binding Domain But Is Not Sufficient for Repression

1987 • 121 citations

Bovine papilloma virus-transformed cells contain multiple E2 proteins.

1988 • 107 citations

A dimer of BPV-1 E2 containing a protease resistant core interacts with its DNA target.

1988 • 99 citations

Functional mapping of the human papillomavirus type 11 transcriptional enhancer and its interaction with the trans-acting E2 proteins.

1988 • 93 citations

Identification of a novel constitutive enhancer element and an associated binding protein: implications for human papillomavirus type 11 enhancer regulation

1989 • 83 citations

Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 trans-activator require an N-terminal amphipathic helix-containing E2 domain.

1988 • 81 citations

A Promoter with an Internal Regulatory Domain Is Part of the Origin of Replication in BPV-1

1987 • 78 citations

Interaction of the bovine papillomavirus type 1 E2 transcriptional control protein with the viral enhancer: purification of the DNA-binding domain and analysis of its contact points with DNA

1988 • 53 citations

Evidence for cooperativity between E2 binding sites in E2 trans-regulation of bovine papillomavirus type 1

1988 • 52 citations

Bovine papilloma virus encoded E2 protein activates lymphokine genes through DNA elements, distinct from the consensus motif, in the long control region of its own genome.

1989 • 37 citations