Ceramide‐induced translocation of protein kinase C ζ in primary cultures of astrocytes

Functions of Ceramide in Coordinating Cellular Responses to Stress

1996 • 1,620 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid.

1995 • 506 citations

Signal transduction through lipid second messengers

1996 • 496 citations

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase.

1994 • 473 citations

Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

1995 • 472 citations

Protein kinase C isozymes and substrates

1996 • 440 citations

Protein kinase C ζ isoform is critical for mitogenic signal transduction

1993 • 383 citations

Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.

1995 • 271 citations

Ceramide signalling and the immune response

1996 • 257 citations

Interaction of protein kinase C ζ with ZIP, a novel protein kinase C-binding protein

1997 • 214 citations

Sphingomyelin breakdown and cell fate

1996 • 212 citations

Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase.

1996 • 193 citations

Expression of Neutral Sphingomyelinase Identifies a Distinct Pool of Sphingomyelin Involved in Apoptosis

1997 • 159 citations

Bidirectional Regulation of Protein Kinase Mζ in the Maintenance of Long-Term Potentiation and Long-Term Depression

1996 • 157 citations

Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C.

1996 • 74 citations

Comparative Study of the Metabolic Pools of Sphingomyelin and Phosphatidylcholine Sensitive to Tumor Necrosis Factor

1996 • 73 citations

Protein kinase C: Ports of anchor in the cell

1996 • 67 citations

Physical association and functional relationship between protein kinase Cζ and the actin cytoskeleton

1995 • 59 citations

Protein kinase C bound to the Golgi apparatus supports the formation of constitutive transport vesicles

1996 • 58 citations

Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-ζ isoform

1994 • 56 citations

Protein kinase C zeta is associated with the mitotic apparatus in primary cell cultures of the shark rectal gland.

1994 • 49 citations

Role of protein kinase C subtypes alpha and delta in the regulation of bradykinin-stimulated phosphoinositide breakdown in astrocytes.

1995 • 48 citations

Modulation of ζ‐Protein Kinase C by Cyclic AMP in PC12 Cells Occurs Through Phosphorylation by Protein Kinase A

1996 • 41 citations

Induction of nerve growth factor synthesis by sphingomyelinase and ceramide in primary astrocyte cultures

1997 • 37 citations

The ζ Isozyme of Protein Kinase C Binds to Tubulin through the Pseudosubstrate Domain

1997 • 29 citations

Phosphatidylcholine‐phospholipase C mediates the induction of nerve growth factor in cultured glial cells

1995 • 16 citations

Ischemia‐Triggered Translocation and Inactivation of Protein Kinase C Isoforms in the Fetal Brain

1995 • 15 citations

Addition of phosphatidylcholine-phospholipase C induces cellular redistribution and phosphorylation of protein kinase C ξ in C 6 glial cells

1996 • 5 citations