Chlorphentermine Suppresses the Phosphatidylinositol Pathway in Concanavalin A-Activated Mouse Splenic Lymphocytes

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1985 • 753 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

Early stimulation of potassium uptake in lymphocytes treated with PHA

1970 • 191 citations

Inhibition of lysosomal phospholipase A and phospholipase C by chloroquine and 4,4'-bis(diethylaminoethoxy) alpha, beta-diethyldiphenylethane.

1980 • 169 citations

Relationship between enhanced turnover of phosphatidylinositol and lymphocyte activation by mitogens

1975 • 153 citations

Histochemical Demonstration of Sites of Choline Esterase Activity.

1948 • 145 citations

Human platelets contain phospholipase C that hydrolyzes polyphosphoinositides.

1983 • 129 citations

Properties of phospholipase C isolated from rat liver lysosomes.

1980 • 128 citations

Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes, and blood leukocytes of patients with amiodarone pulmonary toxicity

1985 • 121 citations

The binding of drugs to different polar lipids in vitro

1979 • 121 citations

Calcium‐dependent activation of lymphocytes by ionophore, A23187, and a phorbol ester tumor promoter

1983 • 120 citations

Advances in immunopharmacology

1982 • 112 citations

Studies on the mechanism of drug-induced lipidosis

1981 • 110 citations

Studies on drug-induced lipidosis: subcellular localization of phospholipid and cholesterol in the liver of rats treated with chloroquine or 4,4'-bis (diethylaminoethoxy)alpha, beta-diethyldiphenylethane.

1980 • 107 citations

NMR-Studies on the molecular basis of drug-induced phospholipidosis—II. Interaction between several amphiphilic drugs and phospholipids

1976 • 106 citations

Inhibition by colchicine of the mitogenic stimulation of lymphocytes prior to the S phase.

1975 • 103 citations

The hydrolysis of phosphatidylinositol by lysosomal enzymes of rat liver and brain

1978 • 99 citations

The Calcium‐Dependent Phosphatidylinositol‐Phosphodiesterase of Rat Brain

1979 • 92 citations

Evidence for Cyclic GMP and Calcium Mediation of Lymphocyte Activation by Mitogens

1977 • 83 citations

Ca replacement by cationic amphiphilic drugs from lipid monolayers

1980 • 82 citations

Drug-induced lipidosis and the alveolar macrophage

1981 • 78 citations

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0

1974 • 70 citations

NMR-Studies on the molecular basis of drug-induced phospholipidosis

1973 • 68 citations

Phosphatidylinositol turnover in mitogen-activated lymphocytes. Suppression by low-density lipoproteins

1980 • 62 citations

Kinetics of colchicine inhibition of mitogenesis in individual lymphocytes

1976 • 62 citations

Molecular studies of the induction of cellular phospholipidosis by cationic amphiphilic drugs.

1984 • 61 citations

Tamoxifen-induced generalized lipidosis in rats subchronically treated with high doses

1981 • 51 citations

A Combination of Calcium Ionophore and 12‐O‐Tetradecanoyl‐Phorbol‐13‐Acetate (TPA) Stimulates the Growth of Purified Resting B Cells

1985 • 39 citations

Cyclosporine does not inhibit mitogen-induced inositol phospholipid degradation in mouse lymphocytes.

1985 • 36 citations

Colchicine inhibits phosphatidylinositol turnover induced in lymphocytes by concavalin A

1977 • 35 citations

Enhanced turnover of arachidonic acid-containing species of phosphatidylinositol and phosphatidic acid of concanavalin astimulated lymphocytes

1984 • 24 citations

Studies on the mechanism of alteration by propranolol and mepacrine of the metabolism of phosphoinositides and other glycerolipids in the rabbit iris muscle

1983 • 22 citations

Antagonism by taxol of effects of microtubule-disrupting agents on lymphocyte cAMP metabolism and cell function.

1984 • 19 citations

Fenfluramine-induced ultrastructural alterations in tissues of rats and guinea pigs

1974 • 19 citations

Phytomitogen-induced stimulation of syntheses de novo of phosphatidylinositol, phosphatidic acid and diacylglycerol in rat and human lymphocytes

1981 • 18 citations

Lipidosis-Like cellular alterations in lymphatic tissues of chlorphentermine-treated animals

1974 • 18 citations

Oncodazole (R 17934) an inhibitor of the turnover of phosphatidyl inositol in concanavalin a induced lymphocytes

1979 • 9 citations

Mrphological and Functional Changes in Mouse Splenic Lymphocytes Following<u>in Vivo</u>and in<u>Vitro</u>Exposure to Chlorphentermine

1986 • 9 citations

Chlorphetermine-induced alterations in the response of human lymphocytes to mitogens

1986 • 2 citations