Regional and neuronal reductions of polyadenylated messenger RNA in Alzheimer's disease
Data up to Jan 2025
Total Citations Per Year
Abstract
References (73)
Basic Methods in Molecular Biology
1986 • 3,284 citations
Diagnosis of Alzheimer's Disease
1985 • 2,482 citations
Greenfield's Neuropathology
1985 • 1,149 citations
Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.
1985 • 979 citations
Basic methods in molecular biology
1987 • 842 citations
Neuron numbers and dendritic extent in normal aging and Alzheimer's disease
1987 • 769 citations
Do the poly(A) tail and 3′ untranslated region control mRNA translation?
1990 • 618 citations
Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices
1987 • 569 citations
The Human Hippocampus
2013 • 551 citations
A NEW DEFINITION OF ALZHEIMER'S DISEASE: A HIPPOCAMPAL DEMENTIA
1985 • 422 citations
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder
1990 • 396 citations
PATHOLOGY OF THE NERVOUS SYSTEM
1949 • 394 citations
Poly(A), poly(A) binding protein and the regulation of mRNA stability
1989 • 355 citations
Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.
1989 • 336 citations
Pathology of the Nervous System
1969 • 284 citations
Biochemistry of Altered Brain Proteins in Alzheimer's Disease
1989 • 261 citations
Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study
1978 • 252 citations
Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age
1985 • 238 citations
Extensive postmortem stability of RNA from rat and human brain
1986 • 226 citations
Selective Disconnection of Specific Visual Association Pathways in Cases of Alzheimer's Disease Presenting with Balint's Syndrome
1990 • 223 citations
The Neuroanatomy of Alzheimer's Disease
1989 • 181 citations
Alzheimer's Disease Brain: Alterations in RNA Levels and in a Ribonuclease-Inhibitor Complex
1984 • 173 citations
The Human Hippocampus
1988 • 170 citations
Genetic Expression in the Developing Brain
1983 • 167 citations
Alzheimer's disease: amyloid plaques in the cerebellum
1989 • 150 citations
Positron Emission Tomography of the Brain
1983 • 145 citations
The Turnover of Messenger RNA
1989 • 136 citations
Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex
1988 • 118 citations
Alzheimer's disease-associated reduction of polysomal mRNA translation
1989 • 113 citations
Alterations in protein synthetic capability of nerve cells in Alzheimer's disease.
1981 • 96 citations
Selective messenger RNA reduction in Alzheimer's disease
1988 • 90 citations
Abnormal processing of multiple proteins in Alzheimer disease.
1989 • 89 citations
Tau in situ hybridization in normal and alzheimer brain: Localization in the somatodendritic compartment
1989 • 88 citations
THE QUANTITATIVE ASSESSMENT OF LIPOFUSCIN PIGMENT, CYTOPLASMIC RNA AND NUCLEOLAR VOLUME IN SENILE DEMENTIA
1978 • 88 citations
Characterization of Messenger RNA from the Cerebral Cortex of Control and Alzheimer‐Afflicted Brain
1986 • 80 citations
RNA and Protein Metabolism in the Aging Brain
1990 • 80 citations
Terminal coma affects messenger RNA detection in post mortem human temporal cortex
1991 • 72 citations
Neuronal RNA in Relation to Neuronal Loss and Neurofibrillary Pathology in the Hippocampus in Alzheimer's Disease
1987 • 70 citations
Characterisation of messenger RNA extracted post-mortem from the brains of schizophrenic, depressed and control subjects.
1988 • 70 citations
Altered Gene Expression in Alzheimer's Disease Brain Tissue
1989 • 64 citations
In situ hybridization histochemistry and the study of gene expression in the human brain
1990 • 62 citations
Increased expression of the embryonic form of a developmentally regulated mRNA in Alzheimer's disease
1990 • 59 citations
Molecular Aspects of Development and Aging of the Nervous System
1989 • 58 citations
Alzheimer's disease: specific increases in a G protein subunit (GSα) mRNA in hippocampal and cortical neurons
1991 • 55 citations
Recovery and measurement of specific RNA species from postmortem brain tissue: A general reduction in Alzheimer's disease detected by molecular hybridization
1986 • 55 citations
Localization and quantitation of 68 kDa neurofilament and superoxide dismutase-1 mRNA in alzheimer brains
1991 • 54 citations
Local Brain Protein Metabolism in Dementia and Schizophrenia: In Vivo Studies with 11C-L-Methionine and Positron Emission Tomography
1983 • 54 citations
Increased muscarinic receptor messenger RNA in Alzheimer's disease temporal cortex demonstrated by in situ hybridization histochemistry
1991 • 53 citations
Increased tau messenger RNA in Alzheimer's disease hippocampus.
1990 • 42 citations
PROTEIN AND NUCLEIC ACID CONTENT IN THE AGING HUMAN BRAIN*
1979 • 33 citations
Distribution of a kainate/ AMPA receptor mRNA in normal and Alzheimer brain
1990 • 31 citations
Quantitative studies of neuronal RNA on the subiculum of demented old individuals
1979 • 31 citations
The use ofin situ hybridization histochemistry for the study of neuropeptide gene expression in the human brain
1990 • 30 citations
Alzheimer’s Disease: Errors in Gene Expression
1985 • 28 citations
Chapter 19 Transcriptional and translational regulatory mechanisms during normal aging of the mammalian brain and in Alzheimer's disease
1986 • 25 citations
The postmortem Alzheimer brain is a source of structurally and functionally intact astrocytic messenger RNA
1988 • 25 citations
Ribonuclease Activities and Distribution in Alzheimer's and Control Brains
1989 • 22 citations
Polyadenylated Messenger RNA in Paired Helical Filament-Immunoreactive Neurons in Alzheimer Disease
1990 • 20 citations
Alzheimer's disease: towards an understanding of the aetiology and pathogenesis
1990 • 18 citations
A study of non-isotopic in situ hybridization histochemistry on postmortem changes in vasopressin mRNA in rat brain
1989 • 18 citations
Polyadenylated Messenger RNA in Paired Helical Filament-Immunoreactive Neurons in Alzheimer Disease
1990 • 17 citations
Brain messenger RNA levels and ribonuclease activity in Alzheimer's disease
1987 • 17 citations
Memory in a Neuron
1989 • 14 citations
Expression of Neuronal mRNAs in Alzheimer Type Degeneration of the Nervous System
1989 • 11 citations
Astrocyte RNA in relation to neuronal RNA depletion in Alzheimer's disease
1988 • 10 citations
Alzheimer's Disease: towards an understanding of the aetiology and pathogenesis
1990 • 10 citations
Neuronal RNA in Pick's and Alzheimer's Diseases
1989 • 10 citations
Gene expression and mental disease
1989 • 9 citations
Strategies for the Identification of Novel Brain Specific Genes Affected in Alzheimer Disease
1989 • 8 citations
Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease
1989 • 8 citations
Role of Ribonuclease and Ribonuclease Inhibitor Activities in Alzheimer's Disease
1989 • 6 citations
Stability of brain RNA post mortem: effect of Alzheimer's disease
1987 • 4 citations
Genetics of the Alzheimer Amyloid Protein Precursor
1990 • 1 citations