Naloxone-reversible effects of d-Ala2-Met5-enkephalinamide-induced behavioral activity in rats

Identification of two related pentapeptides from the brain with potent opiate agonist activity

1975 • 3,780 citations

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

1941 • 3,174 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

1975 • 981 citations

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

1976 • 811 citations

Analgesia induced in vivo by central administration of enkephalin in rat

1976 • 524 citations

The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog.

1976 • 467 citations

[D-Ala ² ]-Met-Enkephalinamide: A Potent, Long-Lasting Synthetic Pentapeptide Analgesic

1976 • 466 citations

Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment

1972 • 439 citations

The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?

1976 • 427 citations

Search for an Endogenous Ligand for the Opiate Receptor

1975 • 315 citations

Enkephalin pentapeptides — A review of current evidence for a physiological role in vertebrate neurotransmission

1977 • 269 citations

Multiple opiate receptors

1980 • 264 citations

Opiate receptor affinities and behavioral effects of enkephalin: Structure-activity relationship of ten synthetic peptide analogues

1976 • 214 citations

Neuroanatomical focus for morphine and enkaphalin-induced hypermotility

1977 • 209 citations

Opiate Effects After Adrenocorticotropin or β-Endorphin Injection in the Periaqueductal Gray Matter of Rats

1978 • 190 citations

Endorphins in Mental Health Research

1980 • 184 citations

Stimulant effects of enkephalin microinjection into the dopaminergic A10 area

1979 • 178 citations

Biogenic amines and narcotic effects. I. Modification of morphine-induced analgesia and motor activity after alteration of cerebral amine levels.

1973 • 172 citations

Behavioural effects in rats of morphine and amphetamine and of a combination of the two drugs

1970 • 167 citations

Opioid Peptides and their Receptors

1982 • 134 citations

Behavioural and pharmacological studies on morphine-induced excitation of rats. Possible relation to brain catecholamines

1973 • 124 citations

Comparison of the behavioral effects of β-endorphin and enkephalin analogs

1977 • 96 citations

MULTIPLE OPIATE RECEPTORS

1978 • 81 citations

Behavioural dissociation of the enkephalinergic systems of nucleus accumbens and nucleus caudatus

1977 • 71 citations

Mixed depressant and stimulant actions of morphine and their relationship to brain acetylcholine

1976 • 71 citations

Behavioral activation by enkephalins in mice

1978 • 70 citations

Endogenous opiates and behavioral responses to environmental novelty

1978 • 59 citations

The effect of acute and chronic naloxone administration on motor activation in the rat

1979 • 58 citations

Behavioral activities of opioid peptides and morphine sulfate in golden hamsters and rats

1979 • 55 citations

Effects of humoral modulators and naloxone on morphine-induced changes in the spontaneous locomotor activity of the rat

1976 • 52 citations

Characteristics of β-endorphin-induced behavioral activation and immobilization

1979 • 49 citations

Possible serotonergic mediation of tonic immobility: Effects of morphine and serotonin blockade

1975 • 47 citations

Evidence for increased apomorphine-sensitive dopaminergic effects after acute treatment with morphine

1977 • 43 citations

Alterations in the effects of dopamine agonists and antagonists on general activity in rats following chronic morphine treatment

1976 • 37 citations

Naltrexone Antagonism of Exploration in the Rat

1979 • 35 citations

Involvement of mesolimbic and extrapyramidal nuclei in the motor depressant action of narcotic drugs

1978 • 32 citations

Acute Effects of Narcotic Analgesics on Behavioral Arousal in the Rat

1973 • 26 citations

Morphine-like analgesic effect of a pituitary hormone, β-lipotropin

1976 • 24 citations

Naltrexone Antagonism of Exploration in the Rat

1979 • 21 citations

Naloxone's antagonism of rigidity but not explosive motor behavior: Possible evidence for two types of mechanisms underlying the actions of opiates and opioids

1978 • 19 citations

The different effect of humoral modulators on the morphine- and central nervous system stimulant-induced hyperactivity of rats

1977 • 15 citations

Cerebral application of enkephalins

1977 • 10 citations

Brain peptides linked to schizophrenia

1976 • 2 citations