Expression Analysis of the Human Caspase-1 Subfamily Reveals Specific Regulation of the CASP5 Gene by Lipopolysaccharide and Interferon-γ

Caspases: Enemies Within

1998 • 6,923 citations

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1999 • 1,540 citations

Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases

1999 • 957 citations

Murine Caspase-11, an ICE-Interacting Protease, Is Essential for the Activation of ICE

1998 • 687 citations

Activation of the STAT Signaling Pathway Can Cause Expression of Caspase 1 and Apoptosis

1997 • 525 citations

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

1999 • 462 citations

Dual Role of Caspase-11 in Mediating Activation of Caspase-1 and Caspase-3 under Pathological Conditions

2000 • 319 citations

A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells.

1995 • 313 citations

Molecular Cloning and Pro-apoptotic Activity of ICErelII and ICErelIII, Members of the ICE/CED-3 Family of Cysteine Proteases

1995 • 281 citations

Caspase knockouts: matters of life and death

1999 • 279 citations

Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene Expression

1997 • 276 citations

Identification and Characterization of ICH-2, a Novel Member of the Interleukin-1β-converting Enzyme Family of Cysteine Proteases

1995 • 262 citations

Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype.

1999 • 233 citations

Identification and Characterization of Ich-3, a Member of the Interleukin-1β Converting Enzyme (ICE)/Ced-3 Family and an Upstream Regulator of ICE

1996 • 231 citations

Purification and catalytic properties of human caspase family members

1999 • 231 citations

Transcriptional regulation of the human prointerleukin 1 beta gene.

1987 • 172 citations

ERICE, a Novel FLICE-activatable Caspase

1998 • 109 citations

ICE, neuronal apoptosis and neurodegeneration

1998 • 105 citations

Involvement of caspase-4(-like) protease in Fas-mediated apoptotic pathway

1997 • 97 citations

Identification of a Cysteine Protease Closely Related to Interleukin‐1β‐Converting Enzyme

1996 • 66 citations

Cyclin D3 Sensitizes Tumor Cells to Tumor Necrosis Factor-Induced, c-Myc-Dependent Apoptosis

1996 • 57 citations

Enzymatic activity of two caspases related to interleukin‐1β‐converting enzyme

1998 • 20 citations