Agonist–antagonist properties of N-allyl-[D-Ala]2-Met-enkephalin

A stereotaxic atlas of the rat brain

1967 • 4,710 citations

Identification of two related pentapeptides from the brain with potent opiate agonist activity

1975 • 3,780 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

Simultaneous quantitative assessment of morphine tolerance and physical dependence.

1969 • 681 citations

Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.

1976 • 639 citations

C fragment of lipotropin has a high affinity for brain opiate receptors

1976 • 488 citations

[D-Ala ² ]-Met-Enkephalinamide: A Potent, Long-Lasting Synthetic Pentapeptide Analgesic

1976 • 466 citations

Enkephalin may mediate euphoria and drive-reduction reward

1977 • 450 citations

Opioid activity of a peptide, beta-lipotropin-(61-91), derived from beta-lipotropin.

1976 • 264 citations

Physical Dependence of Opiate-Like Peptides

1976 • 219 citations

Opiate receptor affinities and behavioral effects of enkephalin: Structure-activity relationship of ten synthetic peptide analogues

1976 • 214 citations

beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.

1976 • 206 citations

Receptor binding and pharmacological activity of opiates in the guinea-pig intestine.

1975 • 182 citations

An Analog of Enkephalin Having Prolonged Opiate-Like Effects in Vivo

1977 • 159 citations

Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions.

1975 • 159 citations

Structural and conformational relationships between the enkephalins and the opiates

1976 • 77 citations

The Search for a Better Analgesic

1973 • 73 citations

Structure-activity relationships of methionine-enkephalin

1976 • 72 citations

beta-Endorphin: behavioral and analgesic activity in cats.

1977 • 62 citations

Discrimination by temperature of opiate agonist and antagonist receptor binding

1975 • 54 citations

Opiate receptor interactions of benzomorphans in rat brain homogenates.

1976 • 51 citations

Homologous N-alkylnorketobemidones. Correlation of receptor binding with analgesic potency

1975 • 43 citations

Correlation of opiate receptor affinity with analgetic effects of meperidine homologs

1976 • 31 citations

Comparison of withdrawal precipitating properties of various morphine antagonists and partial agonists in relation to their stereospecific binding to brain homogenates

1976 • 24 citations

Narcotic agonist and antagonist potencies of a homologous series of N-alkyl-norketobemidones measured by the guinea-pig ileum and mouse vas deferens methods

1975 • 13 citations