Bone marrow chimerism and transplantation tolerance

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen.

1989 • 636 citations

Stable Mixed Hematopoietic Chimerism in DLA-Identical Littermate Dogs Given Sublethal Total Body Irradiation Before and Pharmacological Immunosuppression After Marrow Transplantation

1997 • 633 citations

Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys

1995 • 552 citations

Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen.

1994 • 329 citations

The MHC Reactivity of the T Cell Repertoire Prior to Positive and Negative Selection

1997 • 322 citations

Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

1997 • 317 citations

Presence of hematopoietic stem cells in the adult liver

1996 • 300 citations

The lost chord: microchimerism and allograft survival

1996 • 259 citations

Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen.

1990 • 223 citations

Chimerism and transplantation tolerance: cause and effect

1996 • 217 citations

Skin graft tolerance across a discordant xenogeneic barrier

1996 • 197 citations

MICROCHIMERISM LINKED TO CYTOTOXIC T LYMPHOCYTE FUNCTIONAL UNRESPONSIVENESS (CLONAL ANERGY) IN A TOLERANT RENAL TRANSPLANT RECIPIENT

1995 • 186 citations

MICROCHIMERISM LINKED TO CYTOTOXIC T LYMPHOCYTE FUNCTIONAL UNRESPONSIVENESS (CLONAL ANERGY) IN A TOLERANT RENAL TRANSPLANT RECIPIENT

1995 • 156 citations

HIGH-DOSE DONOR BONE MARROW INFUSIONS TO ENHANCE ALLOGRAFT SURVIVAL

1997 • 136 citations

Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach.

1996 • 132 citations

ADDITIONAL MONOCLONAL ANTIBODY (mAB) INJECTIONS CAN REPLACE THYMIC IRRADIATION TO ALLOW INDUCTION OF MIXED CHIMERISM AND TOLERANCE IN MICE RECEIVING BONE MARROW TRANSPLANTATION AFTER CONDITIONING WITH ANTI-T CELL mABs AND 3-GY WHOLE BODY IRRADIATION1

1996 • 126 citations

c-kit+ stem cells and thymocyte precursors in the livers of adult mice.

1996 • 121 citations

Specific tolerance across a discordant xenogeneic transplantation barrier.

1994 • 118 citations

DEVELOPMENT, STABILITY, AND CLINICAL CORRELATIONS OF ALLOGENEIC MICROCHIMERISM AFTER SOLID ORGAN TRANSPLANTATION1

1996 • 107 citations

Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation.

1993 • 103 citations

Class I-deficient hemopoietic cells and nonhemopoietic cells dominantly induce unresponsiveness of natural killer cells to class I-deficient bone marrow cell grafts.

1997 • 102 citations

The effects of chimeric cells following donor bone marrow infusions as detected by PCR-flow assays in kidney transplant recipients.

1997 • 91 citations

NATURAL KILLER CELLS WEAKLY RESIST ENGRAFTMENT OF ALLOGENEIC, LONG-TERM, MULTILINEAGE-REPOPULATING HEMATOPOIETIC STEM CELLS1

1996 • 87 citations

Missing self recognition by natural killer cells in MHC class I transgenic mice. A ‘receptor calibration’ model for how effector cells adapt to self

1995 • 83 citations

Chimerism and central tolerance

1996 • 82 citations

Successful formation of a chimeric human thymus allograft following transplantation of cultured postnatal human thymus.

1997 • 81 citations

Immune restoration by fetal pig thymus grafts in T cell-depleted, thymectomized mice.

1997 • 78 citations

HUMORAL TOLERANCE IN XENOGENEIC BMT RECIPIENTS CONDITIONED BY A NONMYELOABLATIVE REGIMEN

1992 • 75 citations

ADOPTIVE IMMUNOTHERAPY IN CANINE CHIMERAS1

1997 • 63 citations

PRETRANSPLANT INJECTION OF ALLOGRAFT RECIPIENTS WITH DONOR BLOOD OR LYMPHOCYTES PERMITS ALLOGRAFT TOLERANCE WITHOUT THE PRESENCE OF PERSISTENT DONOR MICROCHIMERISM1

1996 • 50 citations

MODULATORY EFFECTS OF HUMAN DONOR BONE MARROW CELLS ON ALLOGENEIC CELLULAR IMMUNE RESPONSES1

1997 • 46 citations

Is microchimerism needed for allograft tolerance?

1997 • 42 citations

Separate regulation of peripheral hematopoietic and thymic engraftment.

1998 • 41 citations

Host marrow has a competitive advantage that limits donor hematopoietic repopulation in mixed xenogeneic chimeras

1996 • 40 citations

Natural antibodies against bone marrow cells of a concordant xenogeneic species.

1991 • 39 citations

Evidence for nonimmune mechanisms in the loss of hematopoietic chimerism in rat→mouse mixed xenogeneic chimeras

1995 • 37 citations

Hematopoietic cell transplantation for the induction of allo‐ and xenotolerance

1996 • 37 citations

A Synthetic CD4-CDR3 Peptide Analog Enhances Bone Marrow Engraftment Across Major Histocompatibility Barriers

1997 • 34 citations

ORGAN CULTURE FOR THYMUS TRANSPLANTATION1

1996 • 33 citations

The furture of transplantation: With particular reference to chimerism and xenotransplantation

1997 • 30 citations

Mouse natural killer subsets defined by their target specificity and their ability to be separately rendered unresponsive in vivo.

1997 • 29 citations

RECIPIENT PRECONDITIONING AND DONOR-SPECIFIC BONE MARROW INFUSION IN A PIG MODEL OF TOTAL BOWEL TRANSPLANTATION

1997 • 26 citations

A study of tolerance in a concordant xenograft model

1997 • 26 citations

STRIKING AUGMENTATION OF HEMATOPOIETIC CELL CHIMERISM IN NONCYTOABLATED ALLOGENEIC BONE MARROW RECIPIENTS BY FLT3 LIGAND AND TACROLIMUS1

1997 • 20 citations

SECOND-SET REJECTION OF MOUSE LIVER ALLOGRAFTS IS DEPENDENT ON RADIATION-SENSITIVE NONPARENCHYMAL CELLS OF GRAFT BONE MARROW ORIGIN1

1996 • 11 citations