Metabolic alterations in medication-free patients with bipolar disorder: A 3T CSF-corrected magnetic resonance spectroscopic imaging study

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

1996 • 7,011 citations

Comparison of Beck Depression Inventories-IA and-II in Psychiatric Outpatients

1996 • 5,471 citations

Estimation of metabolite concentrations from localized in vivo proton NMR spectra

1993 • 3,535 citations

The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings

2004 • 791 citations

The Altman Self-Rating Mania Scale

1997 • 751 citations

Brain Magnetic Resonance Imaging of Structural Abnormalities in Bipolar Disorder

1999 • 628 citations

Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies

1991 • 625 citations

Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder

2001 • 568 citations

Evidence of Axonal Damage in the Early Stages of Multiple Sclerosis and Its Relevance to Disability

2001 • 507 citations

Evidence for irnnairment of energy metabofism in vivo in Huntington's disease using localized 1H NMR spectroscopy

1993 • 471 citations

Brain Metabolic Alterations in Medication-Free Patients With BipolarDisorder

2004 • 447 citations

MIXOR: a computer program for mixed-effects ordinal regression analysis

1996 • 410 citations

Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2’s neurotrophic effects?

2000 • 398 citations

Rash in Multicenter Trials of Lamotrigine in Mood Disorders

2002 • 334 citations

Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder

2000 • 291 citations

Decreased Anterior Cingulate Myo-inositol/Creatine Spectroscopy Resonance with Lithium Treatment in Children with Bipolar Disorder

2001 • 251 citations

Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: A systematic review of the in vivo proton magnetic resonance spectroscopy findings

2006 • 246 citations

Abnormal cerebral metabolite concentrations in patients with probable alzheimer disease

1994 • 217 citations

Frontal lobe differences in bipolar disorder as determined by proton MR spectroscopy

2002 • 205 citations

Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging

2003 • 198 citations

Choline, myo‐inositol and mood in bipolar disorder: a proton magnetic resonance spectroscopic imaging study of the anterior cingulate cortex

2000 • 193 citations

Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex

2003 • 191 citations

Voxel-based morphometry in adolescents with bipolar disorder: first results

2004 • 189 citations

Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations.

2000 • 182 citations

Proton Magnetic Resonance Spectroscopy of the Frontal Lobe and Cerebellar Vermis in Children with a Mood Disorder and a Familial Risk for Bipolar Disorders

2003 • 163 citations

Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging

1994 • 161 citations

Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders

1998 • 155 citations

Quantitative analysis of short echo time1H-MRSI of cerebral gray and white matter

2000 • 152 citations

Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients

1992 • 148 citations

Lower Concentration of Hippocampal N-Acetylaspartate in Familial Bipolar I Disorder

2003 • 147 citations

Magnetic Resonance Spectroscopy in Affective Disorders

1998 • 135 citations

Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder

1999 • 117 citations

Increased thalamic N-acetylaspartate in male patients with familial bipolar I disorder

2001 • 113 citations

Anatomical MRI study of basal ganglia in bipolar disorder patients

2001 • 111 citations

Reduced NAA Levels in the Dorsolateral Prefrontal Cortex of Young Bipolar Patients

2005 • 102 citations

Changes inN-Acetyl-Aspartate Content during Focal and Global Brain Ischemia of the Rat

1995 • 99 citations

On the N‐acetyl methyl resonance in localized ¹H NMR spectra of human brain In Vivo

1991 • 93 citations

Magnetic Resonance Findings in Bipolar Disorder

2005 • 92 citations

Altered brain energy metabolism in lithium-resistant bipolar disorder detected by photic stimulated ³¹P-MR spectroscopy

2000 • 88 citations

Proton magnetic resonance spectroscopy of the lenticular nuclei in bipolar I affective disorder

1998 • 82 citations

Rationale for long-term treatment of bipolar disorder and evidence for long-term lithium treatment.

2002 • 79 citations

Quantitative in vivo1H nuclear magnetic resonance spectroscopic imaging of neuronal loss in rat brain

1995 • 64 citations

Intracellular phosphatidylinositol pathway abnormalities in bipolar disorder patients.

1997 • 53 citations

Lithium side effects in relation to brain lithium concentration measured by lithium-7 magnetic resonance spectroscopy

1996 • 46 citations

Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects

1997 • 42 citations

N-Acetylaspartate Distribution in Rat Brain Striatum During Acute Brain Ischemia

1999 • 39 citations

Effects of myo-Inositol ingestion on human brain myo-inositol levels: a proton magnetic resonance spectroscopic imaging study

1999 • 36 citations

Untitled

2000 • 26 citations

Lithium and valproate protect against dextro-amphetamine induced brain choline concentration changes in bipolar disorder patients

2004 • 23 citations

Compliance During Lithium Treatment, Intra-Erythrocyte

1991 • 11 citations

Proton MR spectroscopy in psychiatric and neurodevelopmental childhood disorders: early experience.

1998 • 7 citations

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