Angiogenesis in ischemic heart disease

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Angiogenesis.

1992 • 2,581 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1996 • 1,355 citations

Vasculogenesis

1995 • 1,344 citations

The implications of angiogenesis for the biology and therapy of cancer metastasis

1994 • 1,120 citations

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.

1994 • 1,058 citations

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

1996 • 980 citations

Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

1996 • 788 citations

Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.

1994 • 616 citations

Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide.

1995 • 590 citations

Vascular Endothelial Growth Factor, a Potent and Selective Angiogenic Agent

1996 • 570 citations

Salvage of Infarcted Myocardium by Angiogenic Action of Basic Fibroblast Growth Factor

1992 • 519 citations

Meeting Highlights

1996 • 497 citations

Intracoronary gene transfer of fibroblast growth factor–5 increases blood flow and contractile function in an ischemic region of the heart

1996 • 484 citations

Comparative Effects of Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor on Coronary Collateral Development and the Arterial Response to Injury

1996 • 383 citations

Molecular Mechanisms of Coronary Collateral Vessel Growth

1996 • 377 citations

VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis

1996 • 342 citations

Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis

1995 • 330 citations

Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor

1992 • 325 citations

Macrophage-derived angiogenesis factors

1991 • 325 citations

Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts.

1994 • 311 citations

Basic fibroblast growth factor enhances myocardial collateral flow in a canine model

1994 • 304 citations

Possible Participation of Autocrine and Paracrine Vascular Endothelial Growth Factors in Hypoxia-induced Proliferation of Endothelial Cells and Pericytes

1995 • 300 citations

VEGF Improves Myocardial Blood Flow but Produces EDRF-Mediated Hypotension in Porcine Hearts

1996 • 270 citations

Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells.

1995 • 252 citations

Hypotensive Activity of Fibroblast Growth Factor

1991 • 246 citations

Effects of Chronic Systemic Administration of Basic Fibroblast Growth Factor on Collateral Development in the Canine Heart

1995 • 245 citations

Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries.

1992 • 242 citations

Recent insights into coronary collateral circulation.

1992 • 223 citations

Rapid induction of vascular endothelial growth factor expression by transient ischemia in rat heart

1994 • 215 citations

Fibroblast growth factors: at the heart of angiogenesis.

1995 • 190 citations

DNA Synthesis and Mitoses in Coronary Collateral Vessels of the Dog

1971 • 178 citations

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes

1993 • 167 citations

VEGF ₁₆₅ Expressed by a Replication-Deficient Recombinant Adenovirus Vector Induces Angiogenesis In Vivo

1995 • 159 citations

Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium

1993 • 148 citations

Effects of acidic fibroblast growth factor on normal and ischemic myocardium.

1991 • 139 citations

Molecular immunobiology of macrophages: recent progress

1995 • 127 citations

Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes

1993 • 127 citations

An E Box Element Is Required for the Expression of the ad4bp Gene, a Mammalian Homologue of ftz-f1 Gene, Which Is Essential for Adrenal and Gonadal Development

1995 • 124 citations

Enhanced microvascular relaxations to VEGF and bFGF in chronically ischemic porcine myocardium

1996 • 119 citations

Time course of increased cellular proliferation in collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency.

1995 • 109 citations

Exogenous Nitric Oxide Inhibits Proliferation of Cultured Vascular Endothelial Cells

1994 • 99 citations

Basic fibroblast growth factor is cardioprotective in ischemia-reperfusion injury

1995 • 97 citations

Vascular response to basic fibroblast growth factor when infused onto the normal adventitia or into the injured media of the rat carotid artery.

1991 • 92 citations

Cellular adhesion molecules. Newly identified mediators of angiogenesis.

1996 • 76 citations

Preclinical and Clinical Studies with Recombinant Human Basic Fibroblast Growth Factor

1991 • 75 citations

Induction of angiogenesis by smooth muscle cell‐derived factor: Possible role in neovascularization in atherosclerotic plaque

1995 • 75 citations

Macrophages in tissues and in vitro

1992 • 73 citations

Expression of Vascular Endothelial Growth Factor From a Defective Herpes Simplex Virus Type 1 Amplicon Vector Induces Angiogenesis in Mice

1995 • 71 citations

Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation

1994 • 69 citations

A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs

1993 • 49 citations

Cellular Adhesion Molecules

1994 • 40 citations

Comparison of the neovascular effects of stimulated macrophages and neutrophils in autologous rabbit corneas.

1985 • 37 citations

Chronic Hypoxia Increases β ₁ -Adrenergic Receptor mRNA and Density but Not Signaling in Neonatal Rat Cardiac Myocytes

1996 • 31 citations

Extracardiac to coronary anastomoses support regional left ventricular function in dogs

1993 • 24 citations

Expression of angiogenic growth factors in the collateralized swine myocardium

1992 • 21 citations

A novel heart derived inhibitor of vascular cell proliferation. Purification and biological activity

1995 • 9 citations

Perivascular delivery of prolonged half-life aFGF via EVAC results in angiographic collateral development, improvement in coronary flow and function in chronic myocardial ischemia

1996 • 5 citations

Deleted Work

1955 • 0 citations