Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk‐1 receptor

The Biology of Vascular Endothelial Growth Factor

1997 • 4,359 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4

1998 • 1,663 citations

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1995 • 1,272 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.

1999 • 1,044 citations

A requirement for neuropilin-1 in embryonic vessel formation

1999 • 830 citations

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

1993 • 764 citations

Vascular Endothelial Growth Factor Has Neurotrophic Activity and Stimulates Axonal Outgrowth, Enhancing Cell Survival and Schwann Cell Proliferation in the Peripheral Nervous System

1999 • 732 citations

Neuropilin–Semaphorin III/D-Mediated Chemorepulsive Signals Play a Crucial Role in Peripheral Nerve Projection in Mice

1997 • 647 citations

Immunocytochemical Localization of trkA Receptors in Chemically Identified Subgroups of Adult Rat Sensory Neurons

1995 • 622 citations

A Distinct Subgroup of Small DRG Cells Express GDNF Receptor Components and GDNF Is Protective for These Neurons after Nerve Injury

1998 • 617 citations

Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells

1987 • 353 citations

Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: relation of lectin reactivity to peptide and enzyme markers

1990 • 340 citations

Eph receptors and ephrins in neural development

1999 • 330 citations

A monoclonal antibody against neurofilament protein specifically labels a subpopulation of rat sensory neurones

1984 • 306 citations

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF.

1991 • 222 citations

Expression of a Cell Adhesion Molecule, Neuropilin, in the Developing Chick Nervous System

1995 • 200 citations

Angiogenic growth factors

1990 • 192 citations

Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture.

1993 • 190 citations

Vascular endothelial growth factor stimulates Schwann cell invasion and neovascularization of acellular nerve grafts

1999 • 188 citations

NGF and the local control of nerve terminal growth

1994 • 140 citations

Expression of pituitary adenylate cyclase activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla

1996 • 74 citations

Local control of neurite sprouting in cultured sympathetic neurons by nerve growth factor

1987 • 55 citations

A Novel Alternatively Spliced Form of Murine Vascular Endothelial Growth Factor, VEGF 115

1998 • 46 citations

Expression of pituitary adenylate cyclase activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla

1996 • 4 citations