Mice lacking HSP90β fail to develop a placental labyrinth

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

1989 • 624 citations

Essential role of Mash-2 in extraembryonic development

1994 • 612 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.

1996 • 424 citations

Heat-shock protein hsp90 governs the activity of pp60v-src kinase.

1993 • 420 citations

Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β

1997 • 414 citations

Chaperone Function of Hsp90-Associated Proteins

1996 • 376 citations

Purification of the major mammalian heat shock proteins.

1982 • 369 citations

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

1997 • 359 citations

Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.

1992 • 355 citations

Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.

1986 • 338 citations

Capturing genes encoding membrane and secreted proteins important for mouse development.

1995 • 321 citations

Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

1996 • 309 citations

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila

1994 • 294 citations

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone

1997 • 229 citations

Isolation and characterization of a novel trophoblast-specific cDNA in the mouse.

1988 • 193 citations

A New Member of the hsp90 Family of Molecular Chaperones Interacts with the Retinoblastoma Protein during Mitosis and after Heat Shock

1996 • 183 citations

The bHLH-Zip transcription factor Tfeb is essential for placental vascularization

1998 • 179 citations

Retinoid X receptors are essential for early mouse development and placentogenesis

1999 • 176 citations

Ancient heat shock gene is dispensable

1988 • 173 citations

Definition of a Minimal Domain of the Dioxin Receptor That Is Associated with Hsp90 and Maintains Wild Type Ligand Binding Affinity and Specificity

1995 • 164 citations

The Carboxy-Terminal Region of Mammalian HSP90 Is Required for Its Dimerization and Function In Vivo

1994 • 161 citations

Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).

1992 • 155 citations

Murine 86- and 84-kDa Heat Shock Proteins, cDNA Sequences, Chromosome Assignments, and Evolutionary Origins

1989 • 154 citations

Production of completely ES cell-derived fetuses.

1993 • 132 citations

Esx1,a Novel X Chromosome-Linked Homeobox Gene Expressed in Mouse Extraembryonic Tissues and Male Germ Cells

1997 • 110 citations

Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development

1999 • 108 citations

Control of steroid receptor function and cytoplasmic‐nuclear transport by heat shock proteins

1992 • 100 citations

Cloning and Characterization of the Murine Genes for bHLH-ZIP Transcription Factors TFEC and TFEB Reveal a Common Gene Organization for All MiT Subfamily Members

1999 • 95 citations

A role for Hsp90 in retinoid receptor signal transduction.

1995 • 82 citations

The Basic Helix-Loop-Helix/PAS Factor Sim Is Associated with hsp90:

1995 • 76 citations

Efficiency assessment of the gene trap approach

1998 • 71 citations

Germ Line Chimeras from Female ES Cells

1997 • 64 citations

Mutational analysis of Hsp90α dimerization and subcellular localization: dimer disruption does not impede ‘in vivo’ interaction with estrogen receptor

1996 • 64 citations

Fatal gestational choriocarcinoma. Clinicopathologic study of patients treated at a trophoblastic disease center

1982 • 62 citations

Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing

1998 • 45 citations

Distinct functions of the 90 kDa heat-shock protein (hsp90) in oestrogen and mineralocorticosteroid receptor activity: effects of hsp90 deletion mutants

1995 • 44 citations

Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens

1988 • 41 citations

Characterization of the Mouse 84-kD Heat Shock Protein Gene Family

1990 • 21 citations

In vitro study of chorionic and ectoplacental trophoblast differentiation in the mouse

1975 • 19 citations