Fatty acid transport: difficult or easy?

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Relationship Between Carbohydrate and Lipid Metabolism and the Energy Balance of Heart Muscle

1974 • 1,252 citations

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1994 • 854 citations

The Interaction of Human Serum Albumin with Long-chain Fatty Acid Anions

1958 • 743 citations

Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances

1981 • 382 citations

Interactions of long-chain fatty acids and albumin: Determination of free fatty acid levels using the fluorescent probe ADIFAB

1993 • 362 citations

Arachidonic Acid and Other Fatty Acids Directly Activate Potassium Channels in Smooth Muscle Cells

1989 • 353 citations

On the Mechanism of Fatty Acid-induced Proton Transport by Mitochondrial Uncoupling Protein

1996 • 322 citations

Nestlé Nutrition workshop series

1983 • 315 citations

Movement of fatty acids, fatty acid analogs, and bile acids across phospholipid bilayers

1993 • 301 citations

pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids.

1992 • 293 citations

Fatty Acid Flip-Flop in Phospholipid Bilayers Is Extremely Fast

1995 • 289 citations

Mechanism of long chain fatty acid permeation in the isolated adipocyte.

1981 • 262 citations

Inherited Cardiomyopathies

1994 • 256 citations

Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes.

1994 • 237 citations

Hepatocellular uptake of oleate is energy dependent, sodium linked, and inhibited by an antibody to a hepatocyte plasma membrane fatty acid binding protein.

1986 • 210 citations

Effect of fatty acids on H+ transport activity of the reconstituted uncoupling protein.

1994 • 206 citations

Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps

1986 • 197 citations

Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: Inhibition of fatty acid transport

1991 • 191 citations

Mechanism and kinetics of transfer of a fluorescent fatty acid between single-walled phosphatidylcholine vesicles

1980 • 185 citations

Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.

1995 • 184 citations

Transfer of long-chain fluorescent free fatty acids between unilamellar vesicles

1986 • 157 citations

Hydrophobicity of Long Chain n -Alkyl Carboxylic Acids, as Measured by Their Distribution Between Heptane and Aqueous Solutions

1973 • 157 citations

A NMR study of the ionization of fatty acids, fatty amines and N-acylamino acids incorporated in phosphatidylcholine vesicles

1980 • 157 citations

Determinants of intestinal mucosal uptake of short- and medium-chain fatty acids and alcohols

1973 • 150 citations

Solubility of long-chain fatty acids in phosphate buffer at pH 7.4

1992 • 140 citations

Fatty acids in cell signalling: Modulation by lipid binding proteins

1995 • 136 citations

Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites.

1987 • 125 citations

Transbilayer movement of bile acids in model membranes

1987 • 122 citations

Fusion of phosphatidylcholine bilayer vesicles: role of free fatty acid

1978 • 117 citations

Transfer of oleic acid between albumin and phospholipid vesicles.

1986 • 116 citations

Dissociation of Long and Very Long Chain Fatty Acids from Phospholipid Bilayers

1996 • 113 citations

Effects of fatty acids on Na+-Ca2+ exchange and Ca2+ permeability of cardiac sarcolemmal vesicles.

1985 • 110 citations

Rates of hydration of fatty acids bound to unilamellar vesicles of phosphatidylcholine or to albumin

1985 • 110 citations

Biochemistry and biology of plasma lipoproteins

1987 • 109 citations

Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study.

1983 • 106 citations

Fatty Acids Enter Cells by Simple Diffusion

1996 • 104 citations

Uptake of oleate from albumin solutions by rat liver. Failure to detect catalysis of the dissociation of oleate from albumin by an albumin receptor.

1987 • 100 citations

Interfacial ionization and partitioning of membrane-bound local anaesthetics

1992 • 99 citations

Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin.

1996 • 95 citations

Intracellular Fatty-Acid-Binding Proteins Characteristics and Function

1990 • 92 citations

Fatty acid transfer between multilamellar liposomes and fatty acid-binding proteins.

1984 • 88 citations

Interactions of oleic acid with liver fatty acid binding protein: a carbon-13 NMR study

1988 • 82 citations

Spontaneous transfer of monoacyl amphiphiles between lipid and protein surfaces

1997 • 82 citations

A direct role for serum albumin in the cellular uptake of long-chain fatty acids

1995 • 80 citations

A new method for the measurement of dissociation rates for complexes between small ligands and proteins as applied to the palmitate and bilirubin complexes with serum albumin

1974 • 76 citations

Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells

1996 • 72 citations

Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT).

1994 • 71 citations

Free fatty acid perturbation of transmembrane signaling in cytotoxic T lymphocytes.

1989 • 62 citations

Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin

1992 • 62 citations

Transfer of long-chain fluorescent fatty acids between small and large unilamellar vesicles

1993 • 56 citations

Interactions of acyl carnitines with model membranes

2002 • 53 citations

Carbon-13 NMR Spectroscopy of Biological Systems

1995 • 52 citations

A physical-chemical model for cellular uptake of fatty acids: prediction of intracellular pool sizes

1987 • 46 citations

Fatty acids bound to unilamellar lipid vesicles as substrates for microsomal acyl-CoA ligase

1985 • 46 citations

Microscopic studies of fatty acid vesicles

1977 • 41 citations

Carbon-13 NMR spectroscopy of biological systems

1995 • 39 citations

Medium-chain fatty acid binding to albumin and transfer to phospholipid bilayers.

1989 • 39 citations

Unesterified Fatty Acids Inhibit the Binding of Low Density Lipoproteins to the Human Fibroblast Low Density Lipoprotein Receptor

1989 • 38 citations

Introduction How Do Long-Chain Free Fatty Acids Cross Cell Membranes?

1996 • 38 citations

Protein-Mediated Facilitated Uptake Processes for Fatty Acids, Bilirubin, and Other Amphipathic Compounds

1996 • 37 citations

The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane

1996 • 32 citations

Influence of pH of the medium on free fatty acid utilization by isolated mammalian cells

1969 • 29 citations

Polyunsaturated fatty acids in human nutrition

1992 • 29 citations

Calcium-induced fusion of phospholipid vesicles containing free fatty acids: modulation by transmembrane pH-gradients

1992 • 22 citations

Relationship of hepatic cholate transport to regulation of intracellular pH and potassium

1992 • 16 citations

13C NMR Studies of the Interactions of Fatty Acids with Phospholipid Bilayers, Plasma Lipoproteins, and Proteins

1995 • 16 citations

Rapid Transport of Protons across Membranes by Aliphatic Amines and Acids

1995 • 16 citations

Effect of surface and intracellular pH on hepatocellular fatty acid uptake

1996 • 16 citations

Physical properties of fatty acids and their extracellular and intracellular distribution

1992 • 12 citations