Effects of full D1 dopamine receptor agonists on firing rates in the globus pallidus and substantia nigra pars compacta in vivo: tests for D1 receptor selectivity and comparisons to the partial agonist SKF 38393.

Multiple receptors for dopamine

1979 • 3,739 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Molecular biology of dopamine receptors

1992 • 998 citations

SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.

1983 • 886 citations

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

1986 • 742 citations

SCH 23390—The first selective dopamine D-1 antagonist

1983 • 738 citations

Molecular cloning and expression of the gene for a human D1 dopamine receptor

1990 • 675 citations

Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications

1987 • 664 citations

The central effects of a novel dopamine agonist

1978 • 646 citations

Dopamine acts on D2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta.

1987 • 611 citations

Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons

1995 • 542 citations

Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: Light and electron microscopy

1995 • 540 citations

Dopamine Auto- and Postsynaptic Receptors: Electrophysiological Evidence for Differential Sensitivity to Dopamine Agonists

1979 • 502 citations

D₁Receptor Activation Enhances Evoked Discharge in Neostriatal Medium Spiny Neurons by Modulating an L-Type Ca²⁺Conductance

1997 • 492 citations

D1 and D2 dopamine receptor mRNA in rat brain.

1991 • 483 citations

D ₁ Dopamine Receptor Activation Required for Postsynaptic Expression of D ₂ Agonist Effects

1987 • 468 citations

Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis

1990 • 466 citations

Dopaminergic behaviour stereospecifically promoted by the D1 agonist R-SK & F 38393 and selectively blocked by the D1 antagonist SCH 23390

1984 • 351 citations

On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones.

1988 • 336 citations

Obligatory D-1/D-2 receptor interaction in the generation of dopamine agonist related behaviors

1986 • 321 citations

Dopamine D1 receptors facilitate transmitter release

1993 • 260 citations

IMPORTANT CONCEPTS OF RECEPTOR THEORY

1982 • 251 citations

Dopamine receptor agonists: selectivity and dopamine D1 receptor efficacy

1990 • 232 citations

CENTRAL DOPAMINERGIC NEURONS: NEUROPHYSIOLOGICAL IDENTIFICATION AND RESPONSES TO DRUGS**This research was supported by NIMH Grant MH-17871, USPHS Research Scientist Development Award MH-14459 (to G. K. A.), and the State of Connecticut.

1973 • 230 citations

Chronic <scp>L</scp>‐DOPA administration induces dyskinesias in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐treated common marmoset (Callithrix jacchus)

1995 • 215 citations

Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes.

1990 • 208 citations

A10 dopamine neurons: Role of autoreceptors in determining firing rate and sensitivity to dopamine agonists

1984 • 203 citations

Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study

1987 • 193 citations

The induction of grooming and vacuous chewing by a series of selective D-1 dopamine receptor agonists: two directions of D-1:D-2 interaction

1989 • 188 citations

A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets

1992 • 159 citations

Dopamine D1 receptor modulates the voltage‐gated sodium current in rat striatal neurones through a protein kinase A.

1995 • 154 citations

Evidence for the coupling of Gq protein to D1-like dopamine sites in rat striatum: possible role in dopamine-mediated inositol phosphate formation.

1995 • 150 citations

A comparison between dopamine-stimulated adenylate cyclase and 3H-SCH 23390 binding in rat striatum

1985 • 141 citations

Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioural effects and stimulation of adenylate cyclase activity in vitro

1992 • 138 citations

Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

1991 • 137 citations

Agonist and antagonist properties of benzazepine and thienopyridine derivatives at the D1 dopamine receptor

1989 • 131 citations

Characterization of dopamine autoreceptor and [3H]spiperone binding sites in vitro with classical and novel dopamine receptor agonists

1983 • 131 citations

Comparison of effects of D-1 and D-2 dopamine receptor agonists on neurons in the rat caudate putamen: an electrophysiological study

1988 • 126 citations

D1 dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systems

1989 • 124 citations

D₁-like Dopaminergic Activation of Phosphoinositide Hydrolysis Is Independent of D_1ADopamine Receptors: Evidence from D_1AKnockout Mice

1997 • 124 citations

Apomorphine and dopamine D1 receptor agonists increase the firing rates of subthalamic nucleus neurons

1996 • 123 citations

Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation.

1996 • 110 citations

Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist

1989 • 106 citations

Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist.

1992 • 100 citations

Interactions of novel dopaminergic ligands with D-1 and D-2 dopamine receptors

1982 • 93 citations

Dopamine receptor agonist potencies for inhibition of cell firing correlate with dopamine D3 receptor binding affinities

1995 • 86 citations

G protein-coupled inward rectifier modulated by dopamine agonists in cultured substantia nigra neurons

1995 • 79 citations

Dopamine agonists increase pallidal unit activity: Attenuation by agonist pretreatment and anesthesia

1984 • 78 citations

Neurophysiological evidence that D-1 dopamine receptor blockade attenuates postsynaptic but not autoreceptor-mediated effects of dopamine agonists

1986 • 67 citations

Conformational Analysis of D₁ Dopamine Receptor Agonists: Pharmacophore Assessment and Receptor Mapping

1996 • 65 citations

Differential efficacies of dopamine D1 receptor agonists for stimulating adenylyl cyclase in squirrel monkey and rat

1993 • 64 citations

Dopamine autoreceptors and the effects of drugs on locomotion and dopamine synthesis

1985 • 63 citations

Differential modification of striatal D1 dopamine receptors and effector moieties by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo and in vitro.

1987 • 61 citations

Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1982 • 60 citations

Dopamine D1 and D2 receptor agonists induce opposite changes in the firing rate of ventral pallidal neurons

1991 • 60 citations

Effect of dopamine system activation on substantia nigra pars reticulata output neurons: variable single-unit responses in normal rats and inhibition in 6-hydroxydopamine-lesioned rats

1984 • 60 citations

Comparison of [³H]Phosphatidylinositol and [³H]Phosphatidylinositol 4,5‐Bisphosphate Hydrolysis in Postmortem Human Brain Membranes and Characterization of Stimulation by Dopamine D1 Receptors

1997 • 58 citations

Neuronal responses of the globus pallidus to systemic administration of d-amphetamine: investigation of the involvement of dopamine, norepinephrine, and serotonin

1981 • 54 citations

Dopamine D1 receptor desensitization profile in MPTP-lesioned primates

1996 • 53 citations

Differential anti-parkinsonian effects of benzazepine D1 dopamine agonists with varying efficacies in the MPTP-treated common marmoset

1995 • 53 citations

Functional recovery of D1 dopamine receptor-mediated stimulation of rat striatal adenylate cyclase activity following irreversible receptor modification by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): Evidence for spare receptors

1986 • 51 citations

Multiple forms of the D1 dopamine receptor: its linkage to adenylate cyclase and psychopharmacological effects.

1986 • 51 citations

Synergistic interaction between dopamine D-1 and D-2 receptor agonists: circling behaviour of rats with hemitransection

1987 • 49 citations

Behavioral effects in the rat of dihydrexidine, a high-potency, full-efficacy D1 dopamine receptor agonist.

1991 • 48 citations

Effects of dopamine depletion on rotational behavior to dopamine agonists

1983 • 48 citations

Relationship between D 1 dopamine receptors, adenylate cyclase, and the electrophysiological responses of rat nucleus accumbens neurons

1991 • 46 citations

D1 dopamine receptors influence Fos immunoreactivity in the globus pallidus and subthalamic nucleus of intact and nigrostriatal-lesioned rats

1995 • 44 citations

Dopamine D2 receptor control of pallidal fos expression: comparisons between intact and 6-hydroxydopamine-treated hemispheres

1993 • 44 citations

D1 agonist-induced excitation of substantia nigra pars reticulata neurons: mediation by D1 receptors on striatonigral terminals via a pertussis toxin-sensitive coupling pathway

1994 • 43 citations

Neurophysiological investigation of effects of the D‐1 agonist SKF 38393 on tonic activity of substantia nigra dopamine neurons

1987 • 40 citations

The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys

1993 • 38 citations

“Full” dopamine D1 agonists in human caudate: Biochemical properties and therapeutic implications

1995 • 38 citations

Central dopaminergic neurons: Neurophysiological identification and responses to drugs

1973 • 34 citations

Partial and full dopamine D1 agonists produce comparable increases in ventral pallidal neuronal activity: contribution of endogenous dopamine.

1995 • 31 citations

The effect of long-term amphetamine administration on the activity of dopaminergic neurons of the substantia nigra

1980 • 26 citations

SKF 38393 alters the rate‐dependent D2‐mediated inhibition of nigrostriatal but not mesoaccumbens dopamine neurons

1988 • 25 citations

D1 receptor stimulation inhibits dopamine cell activity after reserpine treatment but not after chronic SCH 23390: an effect blocked by N-methyl-D-aspartate antagonists.

1992 • 24 citations

Behavioral Differentiation between Effects elicited at Dopamine D-1 and D-2 Receptors in Rats with Normosensitive DA Receptors

1988 • 16 citations

Differential electrophysiological effects of 3-PPP and its enantiomers on dopamine autoreceptors and postsynaptic receptors

1986 • 12 citations

Enhancement of D₂ receptor agonist‐induced inhibition by D₁ receptor agonist in the ventral tegmental area

1993 • 10 citations

Repeated reserpine treatment alters firing pattern and responses of substantia nigral dopamine neurons

1993 • 9 citations

Inhibition of dopamine synthesis in striatal slices by the D1 agonist SKF 38393 is not mediated by D1 dopamine receptors

1990 • 8 citations

Dihydrexidine, a full D1 dopamine receptor agonist, induces rotational asymmetry in hemiparkinsonian monkeys

1995 • 8 citations

D1 dopamine receptor stimulation inhibits firing activity of midbrain dopamine neurons in reserpine treated rats: An effect eliminated after hemitransection of diencephalon

1996 • 5 citations