A Single Tyrosine of the Interleukin-9 (IL-9) Receptor Is Required for STAT Activation, Antiapoptotic Activity, and Growth Regulation by IL-9

Current protocols in molecular biology

1988 • 4,543 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

Modular binding domains in signal transduction proteins

1995 • 962 citations

Jaks and Stats in signaling by the cytokine receptor superfamily

1995 • 902 citations

An Interleukin-4-Induced Transcription Factor: IL-4 Stat

1994 • 856 citations

The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

1995 • 760 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases

1995 • 713 citations

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.

1995 • 675 citations

Interaction of IL-2Rβ and γ _c Chains with Jak1 and Jak3: Implications for XSCID and XCID

1994 • 647 citations

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

1991 • 597 citations

Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

1994 • 453 citations

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

1996 • 414 citations

Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity.

1988 • 297 citations

Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.

1995 • 291 citations

Identification and purification of human stat proteins activated in response to interleukin-2

1995 • 223 citations

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

1995 • 190 citations

Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex

1995 • 189 citations

Interleukin-9 expression in human malignant lymphomas: unique association with Hodgkin's disease and large cell anaplastic lymphoma

1991 • 173 citations

Expression cloning of the murine and human interleukin 9 receptor cDNAs.

1992 • 155 citations

Interleukin-9 Induces Tyrosine Phosphorylation of Insulin Receptor Substrate-1 via JAK Tyrosine Kinases

1995 • 150 citations

Thymic lymphomas in interleukin 9 transgenic mice.

1994 • 143 citations

JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes.

1994 • 136 citations

Interleukin 4 receptor: signaling mechanisms

1994 • 131 citations

Interleukin-9 and its receptor: involvement in mast cell differentiation and T cell oncogenesis

1995 • 116 citations

A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription.

1995 • 113 citations

Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene

1995 • 93 citations

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor β-chain

1995 • 92 citations

Interleukin-9 is a major anti-apoptotic factor for thymic lymphomas

1995 • 90 citations

Interleukin 9 is expressed by primary and cultured Hodgkin and Reed-Sternberg cells.

1992 • 89 citations

Functional and biochemical characterization of mouse P40/IL-9 receptors.

1990 • 87 citations

Activation of Stat5 by interleukin 2 requires a carboxy-terminal region β chain but is not exxential for the proliferative signal transdution.

1995 • 87 citations

Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor

1992 • 75 citations

EGF Receptor Deletions Define a Region Specifically Mediating Stat Transcription Factor Activation

1995 • 65 citations

Human T cell lines and clones respond to IL-9.

1993 • 57 citations

Interleukin‐9 stimulates in vitro growth of mouse thymic lymphomas

1993 • 47 citations

Interleukin-9

1993 • 35 citations