A metabolic basis for Alzheimer disease.

The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

2002 • 13,092 citations

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

2012 • 10,051 citations

Alzheimer's Disease: The Amyloid Cascade Hypothesis

1992 • 6,649 citations

Oxidative Damage Is the Earliest Event in Alzheimer Disease

2001 • 1,833 citations

Amyloid β-Peptide Impairs Glucose Transport in Hippocampal and Cortical Neurons: Involvement of Membrane Lipid Peroxidation

1997 • 543 citations

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid ß-protein

2001 • 518 citations

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor.

2002 • 497 citations

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation

2003 • 289 citations

Functional mitochondria are required for amyloid β‐mediated neurotoxicity

2001 • 198 citations

Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease

1998 • 190 citations

The glucose transporter of the human brain and blood‐brain barrier

1988 • 144 citations

Dietary Links to Alzheimer's Disease: 1999 Update*

1999 • 132 citations

Abnormality of the α‐ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease

1994 • 99 citations

Diet and Oxidative Stress: A Novel Synthesis of Epidemiological Data on Alzheimer's Disease*

1999 • 79 citations

Cerebrovascular muscle atrophy is a feature of Alzheimer's disease

1998 • 69 citations

Amyloid β-Peptide Inhibits Neuronal Glucose Uptake by Preventing Exocytosis

2001 • 35 citations

Elevated Levels of Tau in Cerebrospinal Fluid: Implications for the Antemortem Diagnosis of Alzheimer's Disease*

1999 • 30 citations

Cholesterol and Cognition

2002 • 25 citations

Endogenous Antioxidant Activities in Relation to Concurrent Vitamins A, C, and E Intake in Dementia

2002 • 24 citations

Neuroimaging and genetic assessment for early diagnosis of Alzheimer's disease.

1996 • 24 citations

Aβpp secretases are co-expressed with Aβpp in the pancreatic islets

2001 • 23 citations

Amyloid β protein precursor metabolism as a modulator of islet β-cell function

2001 • 3 citations

Deleted Work

1955 • 0 citations