Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy

1992 • 1,076 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1993 • 1,026 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors.

1997 • 841 citations

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

1995 • 766 citations

EPIDERMAL-GROWTH-FACTOR RECEPTORS IN HUMAN BLADDER CANCER: COMPARISON OF INVASIVE AND SUPERFICIAL TUMOURS

1985 • 611 citations

Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology.

1993 • 534 citations

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: Induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1997 • 512 citations

Elevated Levels of an Angiogenic Peptide, Basic Fibroblast Growth Factor, in the Urine of Patients With a Wide Spectrum of Cancers

1994 • 478 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

The epidermal growth factor receptor and the prognosis of bladder cancer

1990 • 351 citations

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells

1995 • 336 citations

Fighting Cancer by Attacking its Blood Supply

1996 • 331 citations

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells.

1995 • 317 citations

Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies.

1993 • 245 citations

Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice

1995 • 168 citations

Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique.

1997 • 155 citations

Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A

1996 • 141 citations

Expression of Epidermal Growth Factor Receptor in Invasive Transitional Cell Carcinoma of the Urinary Bladder:A Multivariate Survival Analysis

1994 • 133 citations

Regulation of interleukin-8 expression in human melanoma cells by the organ environment.

1995 • 115 citations

In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals

1995 • 111 citations

Significance of urinary epidermal growth factor and its receptor expression in human bladder cancer.

1997 • 107 citations

Epidermal‐growth‐factor‐receptor expression is associated with rapid tumor proliferation in bladder cancer

1994 • 95 citations

A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas.

1993 • 94 citations

Radical prostatectomy after definitive radiation therapy for prostate cancer

1991 • 86 citations

Treating cancer by inhibiting angiogenesis: new hopes and potential pitfall

1996 • 69 citations

Urinary basic fibroblast growth factor in patients with bladder cancer and benign prostatic hypertrophy

1995 • 67 citations

Amplification and rearrangement of the Kirsten ras oncogene in virus-transformed BALB/c 3T3 cells during malignant tumor progression.

1987 • 58 citations

Bladder cancer: the molecular progression to invasive disease

1994 • 51 citations

Epidermal growth factor receptor-mediated autocrine and paracrine stimulation of human transitional cell carcinoma.

1993 • 49 citations

Raf-1 Protein Kinase Is an Integral Component of the Oncogenic Signal Cascade Shared by Epidermal Growth Factor and Platelet-Derived Growth Factor

1992 • 38 citations

Evaluation of Epidermal Growth Factor Receptor DNA Amplification and mRNA Expression in Bladder Cancer

1992 • 37 citations

Cross talk among tyrosine kinase receptors in PC12 cells: desensitization of mitogenic epidermal growth factor receptors by the neurotrophic factors, nerve growth factor and basic fibroblast growth factor.

1993 • 22 citations

Hypothalamic Mediation of Reduced GH Secretion in Diabetic Rats: Evidence for Reduced Cholinergic Inhibition of Somatostatin Release

1995 • 17 citations

Reappraisal of the Biological Role of Epidermal Growth Factor Receptor in Transitional Cell Carcinoma

1993 • 15 citations

Modulation of the epidermal growth factor receptor by basic fibroblast growth factor

1993 • 12 citations