High branched-chain alpha-keto acid intake, branched-chain alpha-keto acid dehydrogenase activity, and plasma and brain amino acid and plasma keto acid concentrations in rats

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Effects of ingestion of disproportionate amounts of amino acids.

1970 • 1,123 citations

Branched-Chain Amino Acid Metabolism

1999 • 754 citations

Application of high performance liquid chromatography with electrochemical detection to neurochemical analysis: measurement of catecholamines, serotonin and metabolites in rat brain

1981 • 524 citations

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1982 • 445 citations

Metabolism and Clinical Implications of Branched Chain Amino and Keto Acids

1982 • 298 citations

Purification and characterization of branched chain α-keto acid dehydrogenase complex of bovine kidney

1978 • 280 citations

The Effect of a Keto Acid–Amino Acid Supplement to a Restricted Diet on the Progression of Chronic Renal Failure

1984 • 207 citations

Branched-chain amino acid oxidation by isolated rat tissue preparations

1976 • 201 citations

Regulation of branched-chain α-ketoacid dehydrogenase kinase

1984 • 175 citations

Molecular Aspects of Cellular Regulation

1986 • 168 citations

A simplified method for the preparation of 14C-labelled branched-chain α-oxo acids

1972 • 153 citations

Multifunctional control of amino acids of deprivation-induced proteolysis in liver. Role of leucine.

1982 • 139 citations

Regulation of the branched chain 2‐oxoacid dehydrogenase kinase reaction

1982 • 116 citations

Specificity of the effects of leucine and its metabolites on protein degradation in skeletal muscle

1984 • 107 citations

Effects of Leucine on in Vitro Protein Synthesis and Degradation in Rat Skeletal Muscles

1984 • 90 citations

The Use of Ornithine Salts of Branched-Chain Ketoacids in Portal-Systemic Encephalopathy

1980 • 78 citations

Valine metabolism in vivo: Effects of high dietary levels of leucine and isoleucine

1984 • 75 citations

EFFECTS OF α-KETOISOCAPROATE AND OF LEUCINE ON NITROGEN METABOLISM IN POSTOPERATIVE PATIENTS

1983 • 74 citations

Correlations between branched-chain amino acids and branched-chain α-keto acids in blood in maple syrup urine disease

1978 • 68 citations

Leucine and isoleucine activate skeletal muscle branched-chain alpha-keto acid dehydrogenase in vivo

1986 • 66 citations

Effects of dietary protein intake on branched-chain keto acid dehydrogenase activity of the rat. Immunochemical analysis of the enzyme complex.

1988 • 59 citations

Induction of Threonine Imbalance by Dispensable Amino Acids: Relationships Between Tissue Amino Acids and Diet in Rats

1980 • 56 citations

Relationship between Intake and Rate of Oxidation of Leucine and α-Ketoisocaproate In Vivo in the Rat

1984 • 43 citations

Metabolism of 2-oxoacid analogues of leucine, valine and phenylalanine by heart muscle, brain and kidney of the rat☆

1981 • 36 citations

Effects of leucine, isoleucine, or threonine infusion on leucine metabolism in humans

1987 • 36 citations

Activation of Liver Branched-Chain α-Keto Acid Dehydrogenase in Rats by Excesses of Dietary Amino Acids

1985 • 35 citations

Cytosolic and mitochondrial isoenzymes of branched-chain amino acid aminotransferase during development of the rat

1982 • 34 citations

Effect of Dietary Branched-chain α-Keto Acids on Hepatic Branched-chain α-Keto Acid Dehydrogenase in the Rat

1977 • 33 citations

The transport of L-leucine into the brain of the rat in vivo : saturable and non-saturable components of influx

1977 • 31 citations

[24] Estimation of branched-chain α-keto acid dehydrogenase activation in mammalian tissues

1988 • 26 citations

Efficiency of α-Ketoisocaproic Acid as a Substitute for Leucine in the Diet of the Growing Rat

1975 • 24 citations

Nutrition in Renal Failure

1983 • 22 citations

The decarboxylation of α-keto-γ-methiolbutyrate in rat liver mitochondria

1980 • 20 citations

THE INFLUX OF ISOLEUCINE INTO THE CEREBRAL HEMISPHERES AND CEREBELLUM: CARRIER‐MEDIATED TRANSPORT AND DIFFUSION

1977 • 14 citations

Nutritional efficiency of alpha-ketoisocaproate relative to leucine, assessed isotopically

1985 • 14 citations

[7] Measurement of plasma and tissue levels of branched-chain α-keto acids by gas-liquid chromatography

1988 • 11 citations

Comparative studies between rates of incorporation of branched-chain amino acids and their .ALPHA.-ketoanalogues into rat tissue proteins under different dietary conditions.

1984 • 8 citations