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Regulation of branched-chain α-ketoacid dehydrogenase kinase

Data up to Jan 2025

Published1984
Citations175
References47

Total Citations Per Year

Abstract

References (47)

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1982 • 445 citations

Relationship of plasma leucine and α-ketoisocaproate during a L-[1-13C]leucine infusion in man: A method for measuring human intracellular leucine tracer enrichment

1982 • 404 citations

Inhibition of casein kinase II by heparin.

1980 • 341 citations

Splanchnic and peripheral glucose and amino acid metabolism in diabetes mellitus

1972 • 312 citations

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

1975 • 303 citations

Regulation of mammalian pyruvate dehydrogenase

1975 • 299 citations

Oxidation of amino acids by diaphragms from fed and fasted rats

1972 • 232 citations

Branched-chain amino acid oxidation by isolated rat tissue preparations

1976 • 201 citations

Oxidation of Branched Chain Amino Acids by Isolated Hearts and Diaphragms of the Rat

1972 • 195 citations

Effect of leucine and metabolites of branched chain amino acids on protein turnover in heart.

1979 • 188 citations

Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation.

1982 • 172 citations

Blood and tissue branched-chain amino and α-keto acid concentrations: effect of diet, starvation, and disease

1981 • 145 citations

Regulation of leucine and alpha-ketoisocaproic acid metabolism in skeletal muscle. Effects of starvation and insulin.

1980 • 131 citations

Assay of short-chain acyl coenzyme a intermediates in tissue extracts by high-pressure liquid chromatography

1981 • 129 citations

Mechanism of pyruvate inhibition of kidney pyruvate dehydrogenasea kinase and synergistic inhibition by pyruvate and ADP.

1979 • 127 citations

Regulation of the branched chain 2‐oxoacid dehydrogenase kinase reaction

1982 • 116 citations

Purification of rat kidney branched-chain oxo acid dehydrogenase complex with endogenous kinase activity

1982 • 102 citations

Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver

1978 • 102 citations

Aspects of the regulation of the metabolism of branched-chain amino acids

1977 • 102 citations

Activity state of the branched chain α-ketoacid dehydrogenase complex in heart, liver, and kidney of normal, fasted, diabetic, and protein-starved rats

1983 • 99 citations

Effects of L‐leucine and α‐ketoisocaproic acid upon insulin secretion and metabolism of isolated pancreatic islets

1972 • 86 citations

Inhibition of branched chain alpha-ketoacid dehydrogenase kinase activity by alpha-chloroisocaproate.

1982 • 78 citations

Regulation of the branched chain alpha-ketoacid pathway in liver.

1982 • 74 citations

Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats

1975 • 71 citations

Inactivation of purified ox kidney branched‐chain 2‐oxoacid dehydrogenase complex by phosphorylation

1981 • 70 citations

The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation

1981 • 65 citations

Reversible ATP-induced inactivation of branched-chain 2-oxo acid dehydrogenase

1980 • 62 citations

Effects of Branched-chain Amino Acid Antagonism in the Rat on Tissue Amino Acid and Keto Acid Concentrations

1977 • 61 citations

Effect of fasting and fasting-refeeding on conversion of leucine into CO 2 and lipids in rats

1972 • 61 citations

The Effects of Test Doses of Leucine, Isoleucine or Valine on Plasma Amino Acid Levels

1965 • 61 citations

Leucine oxidation in diabetes and starvation: Effects of ketone bodies on branched-chain amino acid oxidation in vitro

1978 • 58 citations

Assessment of Effect of Starvation, Glucose, Fatty Acids and Hormones on α-Decarboxylation of Leucine in Skeletal Muscle of Rat

1976 • 54 citations

Studies on the activation and inactivation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart.

1980 • 51 citations

L-Leucine activates branched chain alpha-keto acid dehydrogenase in rat adipose tissue.

1981 • 44 citations

Regulatory role of dietary leucine on plasma branched-chain amino acid levels in young men.

1976 • 44 citations

Activation of the branched-chain α-ketoacid dehydrogenase complex by a broad specificity protein phosphatase

1982 • 44 citations

Dephosphorylation and reactivation of phosphorylated purified ox‐kidney branched‐chain dehydrogenase complex by co‐purified phosphatase

1983 • 41 citations

The Effect of Octanoate and Palmitate on the Metabolism of Valine in Perfused Hindquarter of Rat

1979 • 38 citations

Studies on the regulation of leucine catabolism

1980 • 36 citations

Studies on the regulation of the branched chain alpha-keto acid dehydrogenase in the perfused rat heart.

1979 • 35 citations

Oxidation of branched-chain amino acids in skeletal muscle and liver of rat Effects of octanoate and energy state

1981 • 32 citations

Effects of α-ketocarboxylic acids and 4-pentenoic acid on insulin secretion from the perfused rat pancreas

1978 • 30 citations

Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle

1982 • 28 citations

Interrelationships between 3‐Hydroxy‐3‐Methylglutaryl‐CoA Synthase, Acetoacetyl‐CoA and Ketogenesis

1981 • 26 citations

Modulation of leucine oxidation and turnover by graded amounts of carbohydrate intake in obese subjects

1982 • 26 citations

Clofibric acid and phenylpyruvic acid as biochemical probes for studying soluble bovine liver branched chain ketoacid dehydrogenase.

1982 • 16 citations

Does leucine- and norleucine-induced insulin release depend on amino acid aminotransferase activity?

1983 • 16 citations

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