Bacterial monocultures, propionate, butyrate and H₂O₂ modulate the expression, secretion and structure of the fasting‐induced adipose factor in gut epithelial cell lines

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Review article: the role of butyrate on colonic function

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TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

2008 • 888 citations

Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

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Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.

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Enterococcus faecalis produces extracellular superoxide and hydrogen peroxide that damages colonic epithelial cell DNA

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The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity

2005 • 420 citations

Absence of intestinal microbiota does not protect mice from diet-induced obesity

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Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation

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Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions

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Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT‐29 selected for growth in sugar‐free medium and its inhibition by glucose

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Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma

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Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice

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Decreased Fat Storage by Lactobacillus Paracasei Is Associated with Increased Levels of Angiopoietin-Like 4 Protein (ANGPTL4)

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The Direct Peroxisome Proliferator-activated Receptor Target Fasting-induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate Treatment

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Rationale for the luminal provision of butyrate in intestinal diseases

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Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness

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Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria

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Fermentation by Gut Microbiota Cultured in a Simulator of the Human Intestinal Microbial Ecosystem Is Improved by Supplementing a Soygerm Powder

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Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids

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Angptl4 Upregulates Cholesterol Synthesis in Liver via Inhibition of LPL- and HL-Dependent Hepatic Cholesterol Uptake

2007 • 189 citations

Epigenetic Regulation of TLR4 Gene Expression in Intestinal Epithelial Cells for the Maintenance of Intestinal Homeostasis

2009 • 171 citations

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

2009 • 158 citations

Oligomerization and Regulated Proteolytic Processing of Angiopoietin-like Protein 4

2004 • 155 citations

Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)

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Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model

2007 • 140 citations

Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by Bifidobacterium adolescentis SPM0212

2008 • 137 citations

Hypoxia Up-regulates Expression of Peroxisome Proliferator-activated Receptor γ Angiopoietin-related Gene (PGAR) in Cardiomyocytes: Role of Hypoxia Inducible Factor 1α

2002 • 137 citations

Enterococcus faecalis from newborn babies regulate endogenous PPARγ activity and IL-10 levels in colonic epithelial cells

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The Angiopoietin-like Proteins ANGPTL3 and ANGPTL4 Inhibit Lipoprotein Lipase Activity through Distinct Mechanisms

2008 • 135 citations

Characteristics of the adhesive determinants of Lactobacillus fermentum 104

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Competition for adhesion between probiotics and human gastrointestinal pathogens in the presence of carbohydrate

2002 • 127 citations

Suppression of the Raf/MEK/ERK Signaling Cascade and Inhibition of Angiogenesis by the Carboxyl Terminus of Angiopoietin-Like Protein 4

2008 • 118 citations

Differential Modulation of Nods Signaling Pathways by Fatty Acids in Human Colonic Epithelial HCT116 Cells

2007 • 113 citations

The acute phase response stimulates the expression of angiopoietin like protein 4

2010 • 113 citations

Lactobacillus crispatus M247-Derived H2O2 Acts as a Signal Transducing Molecule Activating Peroxisome Proliferator Activated Receptor-γ in the Intestinal Mucosa

2008 • 91 citations

Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1α nuclear translocation

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Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1

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The Gut Microbiota

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Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression

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Hypoxia upregulates the expression of angiopoietin‐like‐4 in human articular chondrocytes: Role of angiopoietin‐like‐4 in the expression of matrix metalloproteinases and cartilage degradation

2008 • 65 citations

Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes

2007 • 59 citations

PPARγ is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2

2006 • 57 citations

Development and Characterization of a Model of Liver Metastasis Using Human Colon Cancer HCT-116 Cells

2007 • 50 citations

Determination of Angptl4 mRNA as a Diagnostic Marker of Primary and Metastatic Clear Cell Renal-Cell Carcinoma

2010 • 42 citations

Lipopolysaccharide (LPS) stimulates adipokine and socs3 gene expression in mouse brain and pituitary gland in vivo, and in N-1 hypothalamic neurons in vitro

2009 • 37 citations

Escherichia coli verotoxin 1 mediates apoptosis in human HCT116 colon cancer cells by inducing overexpression of the GADD family of genes and S phase arrest

2005 • 36 citations

Fasting-induced adipose factor/angiopoietin–like protein 4: a potential target for dyslipidemia?

2006 • 33 citations

Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways

2009 • 24 citations

Resveratrol Inhibits Invasion and Metastasis of Hepatocellular Carcinoma Cells

2010 • 18 citations

Regulation of brain-derived resistin and FIAF in a novel hypothalamic neuronal cell line

2006 • 5 citations