Beta‐carotene, carotenoids, and disease prevention in humans

Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence

1992 • 3,313 citations

Clinical Trials: A Practical Approach.

1984 • 2,966 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

β-Carotene: an Unusual Type of Lipid Antioxidant

1984 • 2,147 citations

Nutrition Intervention Trials in Linxian, China: Supplementation With Specific Vitamin/Mineral Combinations, Cancer Incidence, and Disease-Specific Mortality in the General Population

1993 • 1,783 citations

Intake of Carotenoids and Retino in Relation to Risk of Prostate Cancer

1995 • 1,356 citations

Carotenoid content of fruits and vegetables: An evaluation of analytic data

1993 • 862 citations

Analysis of the macular pigment by HPLC: retinal distribution and age study.

1988 • 522 citations

Nutrition Intervention Trials in Linxian, China: Multiple Vitamin/Mineral Supplementation, Cancer Incidence, and Disease-Specific Mortality Among Adults With Esophageal Dysplasia

1993 • 425 citations

Nutrition and lung cancer

1996 • 346 citations

Effect of food preparation on qualitative and quantitative distribution of major carotenoid constituents of tomatoes and several green vegetables

1992 • 346 citations

Carotenoids in the human macula and whole retina.

1988 • 344 citations

Cancer‐Protective Factors in Fruits and Vegetables: Biochemical and Biological Background.

1993 • 336 citations

Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C

1993 • 314 citations

Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses

1995 • 312 citations

Remission of oral leukoplakias and micronuclei in tobacco/betel quid chewers treated with beta‐carotene and with beta‐carotene plus vitamin A

1988 • 273 citations

Sample Size for Studying Intermediate Endpoints within Intervention Trials or Observational Studies

1992 • 246 citations

Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease

1993 • 245 citations

The Linxian Cataract Studies

1993 • 222 citations

Serum carotenoids and coronary heart disease. The Lipid Research Clinics Coronary Primary Prevention Trial and Follow-up Study

1994 • 220 citations

Destruction of tocopherols, carotenoids, and retinol in human plasma by cigarette smoke

1996 • 214 citations

Dietary Beta Carotene and Lung Cancer Risk in U.S. Nonsmokers

1994 • 192 citations

Intake of specific carotenoids and lung cancer risk.

1993 • 186 citations

Response of oral leukoplakia to beta-carotene.

1990 • 172 citations

Attributable risk for oral cancer in northern Italy.

1993 • 142 citations

Saturated Fat Intake and Lung Cancer Risk Among Nonsmoking Women in Missouri

1993 • 136 citations

Serum micronutrients and the subsequent risk of oral and pharyngeal cancer.

1993 • 135 citations

Premorbid Diet and the Prognosis of Women With Breast Cancer

1994 • 135 citations

Beta-Carotene, vitamin A, and lung cancer chemoprevention: results of an intermediate endpoint study

1995 • 122 citations

The Role of Beta‐Carotene in the Prevention of Cardiovascular Disease

1993 • 122 citations

Carotenoids in Erythropoietic Protoporphyria and Other Photosensitivity Diseases

1993 • 116 citations

Benefits and Liabilities of Vitamin A and Carotenoids

1996 • 116 citations

Prooxidant activity of β-carotene under 100% oxygen pressure in rat liver microsomes

1995 • 97 citations

Diet and subsequent survival in women with breast cancer

1994 • 95 citations

Reduction in plasma or Skin Alpha Tocopherol Concentration With Long-term Oral Administration of Beta-carottene in Humans and Mice

1992 • 91 citations

Antioxidant vitamins and coronary artery disease risk

1994 • 84 citations

A clinical trial of antioxidant supplements in the treatment of oral leukoplakia

1994 • 78 citations

The effect of beta-carotene on the regression and progression of cervical dysplasia: A clinical experiment

1991 • 74 citations

The Carotene and Retinol Efficacy Trial (CARET) to prevent lung cancer in high-risk populations: pilot study with cigarette smokers.

1993 • 72 citations

Beta-carotene supplementation in smokers reduces the frequency of micronuclei in sputum

1992 • 68 citations

Changes in serum carotenoids in subjects with colorectal adenomas after 24 mo ofβ-carotene supplementation

1994 • 64 citations

Prevention of cervical intraepithelial neoplasia and cervical cancer

1995 • 53 citations

Treatment of Oral Leukoplakia with Beta-Carotene

1992 • 50 citations

The effect of long-term beta-carotene and vitamin A administration on serum concentrations of alpha-tocopherol.

1994 • 48 citations

The Carotene and Retinol Efficacy Trial (CARET) to prevent lung cancer in high-risk populations: pilot study with asbestos-exposed workers.

1993 • 48 citations

Management of oral mucosal dysplasia with beta-carotene retinoic acid: a pilot cross-over study.

1991 • 48 citations

Steady-State Serum Concentration of Alpha Tocopherol Not Altered by Supplementation With Oral Beta Carotene

1994 • 43 citations

beta-Carotene supplementation results in an increased serum and colonic mucosal concentration of beta-carotene and a decrease in alpha-tocopherol concentration in patients with colonic neoplasia.

1994 • 32 citations