Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by gram-positive bacteria

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Structure and Function of Lipopolysaccharide Binding Protein

1990 • 1,689 citations

Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

1993 • 845 citations

Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice

1996 • 760 citations

Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor

1995 • 754 citations

CD14 Is a pattern recognition receptor

1994 • 706 citations

The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis.

1990 • 367 citations

The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall

1985 • 358 citations

Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes

1994 • 347 citations

Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway

1996 • 325 citations

Gram-positive Organisms and Sepsis

1994 • 314 citations

CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide.

1995 • 303 citations

Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures

1994 • 175 citations

Production of interleukin-1 but not tumor necrosis factor by human monocytes stimulated with pneumococcal cell surface components

1989 • 164 citations

The two soluble forms of the lipopolysaccharide receptor, CD14: Characterization and release by normal human monocytes

1994 • 147 citations

Influence of lipoteichoic acid structure on recognition by the macrophage scavenger receptor

1996 • 135 citations

Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage.

1994 • 98 citations

Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of Streptococcus pneumoniae.

1992 • 97 citations

CD14 is expressed and functional in human B cells

1994 • 54 citations

Monocytes Are the Major Producers of Interleukin-1β in anEx VivoModel of Local Cytokine Production

1995 • 37 citations

In Vitro Effect of Dexamethasone, Pentoxifylline, and Anti-Endotoxin Monoclonal Antibody on the Release of Proinflammatory Mediators by Human Leukocytes Stimulated with Haemophilus influenzae Type B

1994 • 18 citations