Mapping Quantitative Trait Loci Affecting Life History Traits in the Nematode Caenorhabditis elegans

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1982 • 22,508 citations

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1974 • 14,589 citations

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1957 • 4,140 citations

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

Trade-Offs in Life-History Evolution

1989 • 2,647 citations

Acquisition and Allocation of Resources: Their Influence on Variation in Life History Tactics

1986 • 2,279 citations

A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

1992 • 2,057 citations

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1953 • 1,832 citations

Evolution in age-structured populations

1995 • 1,793 citations

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility.

1988 • 958 citations

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1995 • 847 citations

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1975 • 797 citations

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1972 • 731 citations

Aging and resistance to oxidative damage in Caenorhabditis elegans.

1993 • 720 citations

EVOLUTIONARY QUANTITATIVE GENETICS: HOW LITTLE DO WE KNOW?

1989 • 657 citations

Optimally, mutation and the evolution of ageing

1993 • 652 citations

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1980 • 650 citations

Genes that regulate both development and longevity in Caenorhabditis elegans.

1995 • 579 citations

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1991 • 555 citations

A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites.

1992 • 487 citations

GENETICS OF LIFE HISTORY IN DROSOPHILA MELANOGASTER. II. EXPLORATORY SELECTION EXPERIMENTS

1981 • 414 citations

Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing.

1995 • 406 citations

Antagonistic pleiotropy, dominance, and genetic variation

1982 • 402 citations

Simultaneous Tests of Many Hypotheses in Exploratory Research

1982 • 384 citations

OPTIMIZATION MODELS, QUANTITATIVE GENETICS, AND MUTATION

1990 • 383 citations

Oxidative stress and ageing in Caenorhabditis elegans

1993 • 383 citations

Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans.

1979 • 383 citations

GENETICS OF LIFE HISTORY IN DROSOPHILA MELANOGASTER. I. SIB ANALYSIS OF ADULT FEMALES

1981 • 370 citations

Molecular genetics of growth and development in populus. IV. Mapping QTLs with large effects on growth, form, and phenology traits in a forest tree.

1995 • 363 citations

INBREEDING AND LINKAGE

1931 • 320 citations

DIRECT AND CORRELATED RESPONSES TO SELECTION ON AGE AT REPRODUCTION INDROSOPHILA MELANOGASTER

1992 • 311 citations

Production of sperm reduces nematode lifespan

1992 • 301 citations

Pleiotropic models of quantitative variation.

1990 • 294 citations

Estimating genetic correlations from inbred strains

1981 • 286 citations

Evidence for a transposon in caenorhabditis elegans

1983 • 257 citations

Interval mapping of quantitative trait loci for reproductive, morphological, and seed traits of soybean (Glycine max L.)

1993 • 247 citations

Thermotolerance of a Long-lived Mutant of Caenorhabditis elegans

1994 • 208 citations

Antagonistic Pleiotropy, Reversal of Dominance, and Genetic Polymorphism

1994 • 199 citations

Sequence of theC. eleganstransposable element Tcl

1983 • 177 citations

Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans.

1987 • 171 citations

Life history evolution with antagonistic pleiotropy and overlapping generations

1985 • 170 citations

The effects of spontaneous mutation on quantitative traits. I. Variances and covariances of life history traits.

1994 • 168 citations

Parental effects and phenotypic characterization of mutations that affect early development in Caenorhabditis elegans

1980 • 159 citations

High-frequency excision of transposable element Tc1 in the nematode caenorhabditis elegans is limited to somatic cells

1984 • 154 citations

Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation.

1992 • 128 citations

Cloning, sequencing, and mapping of an α‐actinin gene from the nematode Caenorhabditis elegans

1991 • 118 citations

Absence of strong heterosis for life span and other life history traits in Caenorhabditis elegans.

1993 • 104 citations

Maintenance of genetic variability by mutation–selection balance: a child's guide through the jungle

1989 • 103 citations

Pleiotropic models of polygenic variation, stabilizing selection, and epistasis.

1993 • 63 citations

Comparing mutants, selective breeding, and transgenics in the dissection of aging processes ofCaenorhabditis elegans

1993 • 62 citations

Empirical estimates of bonferroni corrections for use in chromosome mapping studies with the BXD recombinant inbred strains

1992 • 57 citations

Epistasis can facilitate the evolution of reproductive isolation by peak shifts: a two-locus two-allele model.

1994 • 57 citations

Quantitative trait loci: individual gene effects on quantitative characters

1993 • 27 citations

Genetic specification of life span and self-fertility in recombinant-inbred strains of Caenorhabditis elegans

1991 • 25 citations

The Effects of Temperature on the Longevity of a Radiation-Sensitive Mutant rad-8 of the Nematode Caenorhabditis elegans

1994 • 21 citations

Tc1(Hin): a form of the transposable element Tc1 in Caenorhabditis elegans

1985 • 14 citations