Back to search

Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation.

Data up to Jan 2025

Published1992
Citations128
References77

Total Citations Per Year

Abstract

References (77)

Introduction to Quantitative Genetics.

1982 • 22,508 citations

The genetical theory of natural selection

1930 • 17,330 citations

THE GENETIC BASIS OF EVOLUTIONARY CHANGE

1975 • 3,588 citations

Natural selection in the wild

1986 • 3,138 citations

The Genetical Theory of Natural Selection.

1931 • 1,638 citations

The Genetic Basis of Evolutionary Change.

1975 • 1,439 citations

Natural Selection in the Wild

1987 • 1,435 citations

A Mathematical Theory of Natural and Artificial Selection, Part V: Selection and Mutation

1927 • 1,336 citations

The causes of molecular evolution

1992 • 1,307 citations

The Genetics of Human Populations

1972 • 1,252 citations

Deleterious mutations and the evolution of sexual reproduction

1988 • 1,130 citations

REGRESSION ANALYSIS OF NATURAL SELECTION: STATISTICAL INFERENCE AND BIOLOGICAL INTERPRETATION

1987 • 919 citations

The Mathematical Theory of Quantitative Genetics.

1987 • 815 citations

The maintenance of genetic variability by mutation in a polygenic character with linked loci

1975 • 797 citations

The genetics of human populations

1974 • 764 citations

The Mathematical Theory of Quantitative Genetics.

1981 • 713 citations

THE GENETIC COVARIANCE BETWEEN CHARACTERS MAINTAINED BY PLEIOTROPIC MUTATIONS

1980 • 707 citations

EVOLUTIONARY QUANTITATIVE GENETICS: HOW LITTLE DO WE KNOW?

1989 • 657 citations

The Effect of Variation of Fitness

1937 • 631 citations

Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle

1984 • 610 citations

MUTATIONS AFFECTING FITNESS IN DROSOPHILA POPULATIONS

1977 • 602 citations

The Causes of Molecular Evolution

1992 • 577 citations

THE MUTATIONAL LOAD WITH EPISTATIC GENE INTERACTIONS IN FITNESS

1966 • 523 citations

Low nucleotide diversity in man.

1991 • 501 citations

MUTATION RATE AND DOMINANCE OF GENES AFFECTING VIABILITY IN DROSOPHILA MELANOGASTER

1972 • 494 citations

THE POPULATION GENETICS OF DROSOPHILA TRANSPOSABLE ELEMENTS

1989 • 442 citations

Mutation-selection balance and the evolutionary advantage of sex and recombination

1990 • 411 citations

Evolutionary genetics

1989 • 381 citations

STRONG NATURAL SELECTION IN A WARNING-COLOR HYBRID ZONE

1989 • 365 citations

Genetic Loads and the Cost of Natural Selection

1970 • 332 citations

Selection against harmful mutations in large sexual and asexual populations

1982 • 326 citations

Heritability of Two Morphological Characters Within and Among Natural Populations of Drosophila melanogaster

1987 • 308 citations

Oscillating selection on Darwin's finches

1987 • 296 citations

Pleiotropic models of quantitative variation.

1990 • 294 citations

Adaptive landscapes, genetic distance and the evolution of quantitative characters

1987 • 258 citations

The rate of polygenic mutation

1988 • 250 citations

Effects of P element insertions on quantitative traits in Drosophila melanogaster.

1992 • 238 citations

RESPONSE TO SELECTION

1955 • 229 citations

Fisher's Theory of Dominance

1929 • 219 citations

Recurrent patterns of natural selection in a population of Darwin's finches

1984 • 210 citations

Predictions of response to artificial selection from new mutations

1982 • 207 citations

Dynamics of polygenic characters under selection

1990 • 195 citations

Strong Natural Selection in a Warning-Color Hybrid Zone

1989 • 184 citations

The effect of selection against extreme deviants based on deviation or on homozygosis

1956 • 180 citations

EFFECTS OF PLEIOTROPY ON PREDICTIONS CONCERNING MUTATION-SELECTION BALANCE FOR POLYGENIC TRAITS

1985 • 178 citations

Genetic loads and estimates of mutation rates in highly inbred plant populations

1990 • 176 citations

Deleterious mutations as an evolutionary factor: 1. The advantage of recombination

1984 • 167 citations

Rates and patterns of scnDNA and mtDNA divergence within the Drosophila melanogaster subgroup.

1988 • 155 citations

SPONTANEOUS MUTATIONS FOR LIFE‐HISTORY CHARACTERS IN AN OBLIGATE PARTHENOGEN

1985 • 151 citations

Multivariate mutation-selection balance with constrained pleiotropic effects.

1989 • 138 citations

Molecular and phenotypic variation in the achaete-scute region of Drosophila melanogaster

1990 • 134 citations

Effect of overall phenotypic selection on genetic change at individual loci.

1978 • 131 citations

Variation maintained in quantitative traits with mutation–selection balance: pleiotropic side-effects on fitness traits

1990 • 124 citations

Maintenance of genetic variability by mutation–selection balance: a child's guide through the jungle

1989 • 103 citations

The divergence of a polygenic system subject to stabilizing selection, mutation and drift

1989 • 93 citations

Quantitative genetic variability maintained by mutation-stabilizing selection balance in finite populations

1988 • 89 citations

COMPETITION BETWEEN METAL TOLERANT AND NORMAL PLANT POPULATIONS ON NORMAL SOIL

1972 • 89 citations

Evolutionary Quantitative Genetics: How Little Do We Know

1989 • 87 citations

QUANTITATIVE VARIATION IN FINITE PARTHENOGENETIC POPULATIONS: WHAT STOPS MULLER'S RATCHET IN THE ABSENCE OF RECOMBINATION?

1990 • 83 citations

Transposition rates of movable genetic elements in Drosophila melanogaster.

1990 • 74 citations

PLEIOTROPIC OVERDOMINANCE AND THE MAINTENANCE OF GENETIC VARIATION IN POLYGENIC CHARACTERS

1984 • 67 citations

Rates of DNA change and phylogeny from the DNA sequences of the alcohol dehydrogenase gene for five closely related species of Hawaiian Drosophila.

1991 • 62 citations

Quantitative genetic variation in body size of mice from new mutations.

1992 • 58 citations

THE MAINTENANCE OF POLYGENIC VARIATION IN FINITE POPULATIONS

1989 • 56 citations

Reproductive fitness and artificial selection in animal breeding: culling on fitness prevents a decline in reproductive fitness in lines of Drosophila melanogaster selected for increased inebriation time

1988 • 55 citations

Spontaneous Mutations for Life-History Characters in an Obligate Parthenogen

1985 • 53 citations

Variation for metrical characters in Drosophila populations III. The nature of selection

1971 • 49 citations

Organization and evolution of the alcohol dehydrogenase gene in Drosophila.

1988 • 40 citations

The quantitative genetic consequences of pleiotropy under stabilizing and directional selection.

1990 • 40 citations

Minor viability mutants in Drosophila.

1979 • 37 citations

Competition Between Metal Tolerant and Normal Plant Populations on Normal Soil

1972 • 31 citations

Quantitative Variation in Finite Parthenogenetic Populations: What Stops Muller's Ratchet in the Absence of Recombination?

1990 • 31 citations

The Population Genetics Of Drosophila Transposable Elements

1989 • 30 citations

The maintenance of the genetic variability of polygenic characters by heterozygous advantage

1973 • 27 citations

The maintenance of genetic variability by mutation in a polygenic character with linked loci

2007 • 27 citations

Pleiotropy and multilocus polymorphisms.

1992 • 14 citations

Second-order approximations for selection coefficients at polygenic loci

1990 • 9 citations

Cited By (0)

Loading...
Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative… (1992) – Genetics | Metascience Observatory Explorer