The T cell death knell: immune-mediated tumor death in renal cell carcinoma.

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

1995 • 2,142 citations

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1997 • 749 citations

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

1996 • 368 citations

Caspase-independent Cell Killing by Fas-associated Protein with Death Domain

1998 • 317 citations

Granzyme A Loading Induces Rapid Cytolysis and a Novel Form of DNA Damage Independently of Caspase Activation

1999 • 238 citations

Target Cell Lysis by CTL Granule Exocytosis Is Independent of ICE/Ced-3 Family Proteases

1997 • 237 citations

Entry and Trafficking of Granzyme B in Target Cells During Granzyme B-Perforin–Mediated Apoptosis

1998 • 210 citations

Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases)

1997 • 198 citations

Fas-mediated apoptosis in human prostatic carcinoma cell lines.

1997 • 189 citations

Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells.

1997 • 183 citations

Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.

1996 • 169 citations

Cytotoxic T Lymphocyte-assisted Suicide

1998 • 161 citations

Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases

1998 • 144 citations

Dead or dying: necrosis versus apoptosis in caspase-deficient human renal cell carcinoma.

1999 • 82 citations

Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes

1999 • 26 citations