Regulation of Global and Specific mRNA Translation by Amino Acids

Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

2000 • 3,071 citations

Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism

1998 • 1,319 citations

Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

2000 • 783 citations

Upstream Open Reading Frames as Regulators of mRNA Translation

2000 • 728 citations

Control of p70 S6 kinase by kinase activity of FRAP in vivo

1995 • 717 citations

Regulation of eIF-4E BP1 Phosphorylation by mTOR

1997 • 511 citations

Bidirectional modulation of insulin action by amino acids.

1998 • 491 citations

Orally Administered Leucine Stimulates Protein Synthesis in Skeletal Muscle of Postabsorptive Rats in Association with Increased eIF4F Formation

2000 • 471 citations

Leucine Regulates Translation of Specific mRNAs in L6 Myoblasts through mTOR-mediated Changes in Availability of eIF4E and Phosphorylation of Ribosomal Protein S6

1999 • 356 citations

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

2000 • 338 citations

Amino acid availability regulates p70 S6 kinase and multiple translation factors

1998 • 331 citations

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

1999 • 276 citations

A Mammalian Homologue of GCN2 Protein Kinase Important for Translational Control by Phosphorylation of Eukaryotic Initiation Factor-2α

2000 • 276 citations

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis.

1987 • 257 citations

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2α kinase

1999 • 254 citations

Branched-chain Amino Acids Are Essential in the Regulation of PHAS-I and p70 S6 Kinase by Pancreatic β-Cells

1998 • 236 citations

Implication of eIF2B Rather Than eIF4E in the Regulation of Global Protein Synthesis by Amino Acids in L6 Myoblasts

1998 • 166 citations

Internal Ribosome Entry Site-mediated Translation of a Mammalian mRNA Is Regulated by Amino Acid Availability

2001 • 156 citations

Amino acid effects on translational repressor 4E-BP1 are mediated primarily by<scp>l</scp>-leucine in isolated adipocytes

1998 • 150 citations

Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process

2000 • 131 citations

Amino acids stimulate phosphorylation of p70 ^S6k and organization of rat adipocytes into multicellular clusters

1998 • 130 citations

Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs

2000 • 107 citations

Physiological stresses inhibit guanine‐nucleotide‐exchange factor in Ehrlich cells

1988 • 104 citations

Modulation of Translation Initiation in Rat Skeletal Muscle and Liver in Response to Food Intake

1997 • 88 citations

Stimulative Effect of Dietary Protein on the Phosphorylation of p70 S6 Kinase in the Skeletal Muscle and Liver of Food-deprived Rats

1999 • 26 citations