Mitochondrial nitric oxide inhibits ATP synthesis Effect of free calcium in rat heart

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Mitochondrial free radical generation, oxidative stress, and aging11This article is dedicated to the memory of our dear friend, colleague, and mentor Lars Ernster (1920–1998), in gratitude for all he gave to us.

2000 • 2,864 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

Nitric Oxide Synthases: Properties and Catalytic Mechanism

1995 • 1,275 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

1994 • 1,026 citations

Methods in nitric oxide research

1996 • 826 citations

Nitric Oxide Inhibits Electron Transfer and Increases Superoxide Radical Production in Rat Heart Mitochondria and Submitochondrial Particles

1996 • 726 citations

Endothelium‐derived nitric oxide: actions and properties

1989 • 686 citations

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.

1996 • 677 citations

Nitric oxide synthase activity in mitochondria

1997 • 576 citations

Production of Nitric Oxide by Mitochondria

1998 • 573 citations

Redox‐dependent signal transduction

2000 • 558 citations

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase

1995 • 540 citations

Physiologic Mechanisms of Postischemic Tissue Injury

1995 • 427 citations

Oxygen-derived radicals: a link between reperfusion injury and inflammation.

1987 • 389 citations

Modulation of Mitochondrial Function by Hydrogen Peroxide

2001 • 374 citations

Relation between mitochondrial calcium transport and control of energy metabolism

1985 • 362 citations

Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

2001 • 339 citations

Mitochondrial Nitric-oxide Synthase Stimulation Causes Cytochrome c Release from Isolated Mitochondria

1999 • 333 citations

Purification and Characterization of a Nitric-oxide Synthase from Rat Liver Mitochondria

1998 • 329 citations

Nitric Oxide Potently and Reversibly Deenergizes Mitochondria at Low Oxygen Tension

1994 • 324 citations

Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose

1996 • 320 citations

Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization

1999 • 311 citations

Mitochondrial Nitric Oxide Synthase: A Ubiquitous Regulator of Oxidative Phosphorylation?

1996 • 244 citations

Endogenous nitric oxide synthase inhibitors are responsible for the <scp>L</scp>‐arginine paradox

2000 • 240 citations

Functional implications of nitric oxide produced by mitochondria in mitochondrial metabolism

1998 • 221 citations

Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration

1995 • 207 citations

Immunocytochemical Evidence for a Mitochondrially Located Nitric Oxide Synthase in Brain and Liver

1995 • 204 citations

Redox Regulatory Mechanisms of Cellular Signal Transduction

2000 • 186 citations

Structural and Functional Characterization of Human NAD Kinase

2001 • 166 citations

Biosynthesis and Palmitoylation of Endothelial Nitric Oxide Synthase: Mutagenesis of Palmitoylation Sites, Cysteines-15 and/or -26, Argues against Depalmitoylation-Induced Translocation of the Enzyme

1995 • 127 citations

Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite

1996 • 116 citations

Release of cytochrome c from heart mitochondria is induced by high Ca2+ and peroxynitrite and is responsible for Ca2+-induced inhibition of substrate oxidation

1999 • 116 citations

Effects of the Reactive Oxygen Species Hydrogen Peroxide and Hypochlorite on Endothelial Nitric Oxide Production

2001 • 107 citations

Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells

2002 • 94 citations

The assumption that nitric oxide inhibits mitochondrial ATP synthesis is correct

1999 • 90 citations

Cationic amino acid transporter gene expression in cultured vascular smooth muscle cells and in rats

1999 • 82 citations

Transmembrane signalling mechanisms regulating expression of cationic amino acid transporters and inducible nitric oxide synthase in rat vascular smooth muscle cells

1999 • 56 citations

Kinetic Analysis of Changes in Activity of Heart Mitochondrial Oxidative Phosphorylation System Induced by Ischemia

1996 • 48 citations

Bioenergetics in cardiac hypertrophy: mitochondrial respiration as a pathological target of NO·

2001 • 43 citations

Potassium Collapses the ΔPin Yeast Mitochondria While the Rate of ATP Synthesis Is Inhibited Only Partially: Modulation by Phosphate

1997 • 27 citations

Regulation of the rate of synthesis of nitric oxide by Mg 2+ and hypoxia. Studies in rat heart mitochondria

2002 • 22 citations

Role of intramitochondrial nitric oxide in rat heart and kidney during hypertension

2002 • 15 citations

Reactivity of the H+-ATPase from Kluyveromyces lactis to Sulfhydryl Reagents

1995 • 9 citations

Nitric oxide in the nervous system

1999 • 8 citations