Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Oxygen activation and the conservation of energy in cell respiration

1992 • 1,121 citations

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

1994 • 1,026 citations

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.

1990 • 751 citations

Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism.

1990 • 690 citations

Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.

1988 • 592 citations

Studies on Cytochrome Oxidase

1961 • 516 citations

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated in the nitric oxide/oxygen reaction

1993 • 474 citations

Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.

1986 • 421 citations

Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat

1990 • 399 citations

Reactions of cytochrome oxidase with oxygen and carbon monoxide

1963 • 382 citations

Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cells.

1982 • 349 citations

Cytochrome oxidase : a synthesis

1981 • 334 citations

Reactions of nitric oxide with cytochrome c oxidase

1980 • 232 citations

Structural features and the reaction mechanism of cytochrome oxidase: iron and copper X-ray absorption fine structure

1981 • 228 citations

Iron depletion: Possible cause of tumor cell cytotoxicity induced by activated macrophages

1984 • 183 citations

Cytochrome Oxidase, A Synthesis

1982 • 167 citations

A re-examination of the reactions of cyanide with cytochrome c oxidase

1984 • 149 citations

Oxygen Binding and Activation: Early Steps in the Reaction of Oxygen with Cytochrome c Oxidase

1994 • 141 citations

Structure of cytochrome a3-Cua3 couple in cytochrome c oxidase as revealed by nitric oxide binding studies.

1979 • 112 citations

The steady-state kinetics of cytochrome c oxidation by cytochrome oxidase

1990 • 98 citations

How does NO activate hemeproteins?

1994 • 85 citations

Mitochondrial iron loss from leukemia cells injured by macrophages. A possible mechanism for electron transport chain defects.

1988 • 85 citations

A plausible two-state model for cytochrome c oxidase.

1981 • 85 citations

Structure and function of cytochrome oxidase: a second look.

1988 • 22 citations