Glutathione transferase Zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A manual of biochemical methods

1984 • 612 citations

Water Chlorination — Chemistry, Environmental Impact and Health Effects

1986 • 529 citations

Zeta, a novel class of glutathione transferases in a range of species from plants to humans

1997 • 498 citations

The pharmacology of dichloroacetate

1989 • 477 citations

Differential analyses of glyoxylate derivatives

1970 • 330 citations

Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate

1990 • 295 citations

The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver

1987 • 277 citations

The carcinogenicity of dichloroacetic acid in the male fischer 344 rat

1996 • 157 citations

Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice

1992 • 155 citations

Novel metabolites of trichloroethylene through dechlorination reactios in rats, mice and humans

1984 • 122 citations

Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.

1990 • 89 citations

Glutathione-dependent conversion to glyoxylate, a major pathway of dichloroacetate biotransformation in hepatic cytosol from humans and rats, is reduced in dichloroacetate-treated rats.

1997 • 53 citations

Dichloroacetic acid: metabolism in cytosol.

1995 • 44 citations

Tissue distribution, excretion, and urinary metabolites of dichloroacetic acid in the male fischer 344 rat

1993 • 37 citations

Absence of Mutagenic Effects of Sodium Dichloroacetate

1996 • 35 citations

Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats

1995 • 33 citations

Kinetics and Metabolism of Chloral Hydrate in Children: Identification of Dichloroacetate as a Metabolite

1997 • 28 citations

Bioactivation of [13C]Dichloromethane in Mouse, Rat, and Human Liver Cytosol: 13C Nuclear Magnetic Resonance Spectroscopic Studies

1994 • 25 citations

Protective effect of dichloroacetate in a rat model of forebrain ischemia

1996 • 25 citations