The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

1981 • 4,191 citations

Origin of Concatemeric T7DNA

1972 • 1,591 citations

Nucleotide sequence and organization of the adeno-associated virus 2 genome

1983 • 716 citations

Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells.

1982 • 456 citations

A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication

1987 • 442 citations

Adeno-associated virus general transduction vectors: analysis of proviral structures

1988 • 347 citations

Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants

1984 • 303 citations

Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV

1983 • 300 citations

Adenovirus DNA replication in vitro.

1979 • 294 citations

Palindromic base sequences and replication of eukaryote chromosome ends

1974 • 280 citations

Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function

1984 • 279 citations

Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA

1980 • 228 citations

Replication of adeno-associated virus in synchronized cells without the addition of a helper virus

1987 • 218 citations

Adeno-Associated Viruses: An Update

1987 • 209 citations

Concatemers of alternating plus and minus strands are intermediates in adenovirus-associated virus DNA synthesis.

1976 • 204 citations

Positive and negative autoregulation of the adeno-associated virus type 2 genome

1986 • 194 citations

Vaccinia virus, herpes simplex virus, and carcinogens induce DNA amplification in a human cell line and support replication of a helpervirus dependent parvovirus

1986 • 190 citations

In vitro resolution of covalently joined AAV chromosome ends

1990 • 163 citations

Factors that bind to adeno-associated virus terminal repeats

1989 • 161 citations

Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein

1989 • 161 citations

Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript

1988 • 157 citations

Origin and termination of adeno-associated virus DNA replication

1977 • 157 citations

Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product.

1986 • 155 citations

Identification of the trans-acting Rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptide

1986 • 147 citations

Adeno-Associated Virus Gene Expression Inhibits Cellular Transformation by Heterologous Genes

1987 • 128 citations

Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein

1988 • 125 citations

Complete nucleotide sequence and genome organization of bovine parvovirus

1986 • 125 citations

The NS-1 polypeptide of minute virus of mice is covalently attached to the 5' termini of duplex replicative-form DNA and progeny single strands

1988 • 124 citations

The adeno-Associated virus Rep78 gene inhibits cellular transformation induced by bovine papillomavirus

1989 • 124 citations

A genome-linked copy of the NS-1 polypeptide is located on the outside of infectious parvovirus particles

1989 • 120 citations

Adeno-Associated Viruses

1979 • 118 citations

Sequence analysis of the termini of virion and replicative forms of minute virus of mice DNA suggests a modified rolling hairpin model for autonomous parvovirus DNA replication

1985 • 117 citations

Replication of adeno-associated virus DNA

1984 • 108 citations

Identification of nuclear proteins that specifically interact with adeno-associated virus type 2 inverted terminal repeat hairpin DNA

1989 • 92 citations

Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation

1988 • 89 citations

Sequence and symmetry requirements within the internal palindromic sequences of the adeno-associated virus terminal repeat

1988 • 81 citations

Characterization of adeno-associated virus rep proteins in human cells by antibodies raised against rep expressed in Escherichia coli

1987 • 80 citations

Structural and Functional Homology of Parvovirus and Papovavirus Polypeptides

1987 • 71 citations

Covalent association of protein with replicative form DNA of parvovirus H-1.

1979 • 66 citations

Adeno-associated virus gene expression inhibits cellular transformation by heterologous genes.

1987 • 64 citations

Conformation Takes Precedence over Sequence in Adeno-Associated Virus DNA Replication

1984 • 58 citations

Structure and nucleotide sequence of the terminal regions of adeno-associated virus DNA

1977 • 53 citations

In vitro excision of adeno-associated virus DNA from recombinant plasmids: isolation of an enzyme fraction from HeLa cells that cleaves DNA at poly(G) sequences.

1988 • 45 citations

Inverted terminal repetition in adeno-associated virus DNA: independence of the orientation at either end of the genome

1981 • 43 citations

Cloning of adeno-associated virus into pBR322: Rescue of intact virus from the recombinant plasmid in human cells

1982 • 27 citations

Conformation takes precedence over sequence in adeno-associated virus DNA replication.

1984 • 24 citations

Proteins tightly associated with the termini of replicative form DNA of Kilham rat virus, an autonomous parvovirus.

1985 • 12 citations