BCR-ABL gene rearrangement and expression of primitive hematopoietic progenitors in chronic myeloid leukemia

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Genomic sequencing.

1984 • 8,343 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

1977 • 888 citations

The Chronic Myelogenous Leukemia-Specific P210 Protein Is the Product of the bcr / abl Hybrid Gene

1986 • 820 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Separation of pluripotent haematopoietic stem cells from spleen colony-forming cells

1990 • 414 citations

Evolution of the Functional Human β-Actin Gene and Its Multi-Pseudogene Family: Conservation of Noncoding Regions and Chromosomal Dispersion of Pseudogenes

1985 • 378 citations

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

1991 • 353 citations

Long-Term Marrow Culture Reveals Chromosomally Normal Hematopoietic Progenitor Cells in Patients with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia

1983 • 335 citations

Clinical investigation of human alpha interferon in chronic myelogenous leukemia

1987 • 332 citations

Removal of repeated sequences from hybridisation probes

1985 • 293 citations

PCR-based cDNA library construction: general cDNA libraries at the level of a few cells

1989 • 285 citations

Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells.

1989 • 281 citations

Chronic myelogenous leukemia: recent advances

1985 • 247 citations

Involvement of the B-lymphoid system in chronic myelogenous leukaemia

1980 • 240 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression

1992 • 202 citations

Chronic myelogenous leukemia: recent advances

1985 • 190 citations

Growth characteristics of leukemic and normal hematopoietic cells in Ph' + chronic myelogenous leukemia and effects of intensive treatment

1982 • 159 citations

Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression

1992 • 156 citations

Origin of Chronic Myelocytic Leukemia in a Precursor of Pre-B Lymphocytes

1979 • 113 citations

Rearrangement of the bcr Gene in Philadelphia-Chromosome-Negative Chronic Myeloid Leukemia

1987 • 103 citations

Rearrangement of the bcr gene in Philadelphia chromosome-negative chronic myeloid leukemia

1986 • 85 citations

Characterization of N-myc amplification units in human neuroblastoma cells.

1988 • 51 citations

Variability in 4-hydroperoxycyclophosphamide activity during clinical purging for autologous bone marrow transplantation

1987 • 45 citations

PCR-based cDNA library construction: general cDNA libraries at the level of a few cells

1989 • 22 citations

Variability in 4-hydroperoxycyclophosphamide activity during clinical purging for autologous bone marrow transplantation

1987 • 5 citations