Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

A simple fluorometric assay for lipoperoxide in blood plasma

1976 • 2,101 citations

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

1984 • 1,631 citations

Electrophoretic separation of plasma lipoproteins in agarose gel

1968 • 1,332 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.

1984 • 826 citations

Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products.

1987 • 625 citations

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.

1980 • 586 citations

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

1984 • 547 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells.

1986 • 516 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

Enhanced macrophage degradation of biologically modified low density lipoprotein.

1983 • 469 citations

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing

1983 • 467 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein.

1985 • 388 citations

A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo

1983 • 317 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. IV. Investigation of macrophage-like properties of aortic cell populations.

1979 • 297 citations

Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases.

1985 • 282 citations

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

1978 • 276 citations

Superoxide initiates oxidation of low density lipoprotein by human monocytes.

1987 • 273 citations

Nonenzymatic cleavage of proteins by reactive oxygen species generated by dithiothreitol and iron.

1985 • 268 citations

Why does Coomassie Brilliant Blue R interact differently with different proteins? A partial answer.

1985 • 266 citations

Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system.

1983 • 266 citations

Hormone and neurotransmitter receptors in an established vascular endothelial cell line.

1976 • 257 citations

Copper salt-dependent hydroxyl radical formation

1983 • 242 citations

Modification of human low-density lipoprotein by the lipid peroxidation product 4-hydroxynonenal

1986 • 241 citations

Unusual copper-induced sensitization of the biological damage due to superoxide radicals.

1981 • 240 citations

Oxygen Effect in the Radiolysis of Proteins

1984 • 220 citations

Damage to proteins, enzymes, and amino acids by peroxidizing lipids

1966 • 214 citations

Role of lysines in mediating interaction of modified low density lipoproteins with the scavenger receptor of human monocyte macrophages.

1984 • 213 citations

Site-specific modification of albumin by free radicals. Reaction with copper(II) and ascorbate

1986 • 212 citations

Processing of Apolipoprotein B-100 of Human Plasma Low Density Lipoproteins by Tissue and Plasma Kallikreins

1986 • 201 citations

Sensitized photooxidation of histidine and its derivatives. Products and mechanism of the reaction

1969 • 199 citations

Free-radical damage to lipids, amino acids, carbohydrates and nucleic acids determined by thiobarbituric acid reactivity

1982 • 197 citations

Hemin-mediated oxidative degradation of proteins.

1984 • 173 citations

Polymerization of proteins induced by free-radical lipid peroxidation

1966 • 172 citations

Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor.

1987 • 171 citations

Degradation of apolipoprotein B-100 of human plasma low density lipoproteins by tissue and plasma kallikreins.

1984 • 165 citations

The analogous mechanisms of enzymatic inactivation induced by ascorbate and superoxide in the presence of copper.

1983 • 165 citations

Uptake and degradation of low density lipoprotein by swine arterial smooth muscle cells with inhibition of cholesterol biosynthesis

1976 • 153 citations

Intracellular protein catabolism

1977 • 118 citations

Properties of apolipoprotein b in urea and in aqueous buffers the use of glutathione and nitrogen in its solubilization

1981 • 116 citations

Non-enzymatic degradation of acid-soluble calf skin collagen by superoxide ion: Protective effect of flavonoids

1983 • 115 citations

Oxygen Effect in the Radiolysis of Proteins

1980 • 106 citations

Scavenger receptor-mediated recognition of maleyl bovine plasma albumin and the demaleylated protein in human monocyte macrophages.

1985 • 101 citations

Degradation of soluble collagen by ozone or hydroxyl radicals

1984 • 81 citations

Potentiation of free radical-induced lipid peroxidative injury to sarcolemmal membranes by lipid amphiphiles.

1986 • 80 citations

Studies of the limited degradation of mucus glycoproteins. The effect of dilute hydrogen peroxide

1983 • 70 citations

Demonstration of a protease‐like activity in human serum low density lipoprotein

1974 • 52 citations

INHIBITION BY BACITRACIN OF SOME HYDROLYTIC ENZYMES

1972 • 34 citations

Stability of the apoprotein of human serum low density lipoprotein: Absence of endogenous endopeptidase activity

1975 • 33 citations

Fragmentation of extracellular and intracellular polypeptides by free radicals.

1985 • 31 citations

Structure and function of human low density lipoproteins. Studies using proteolytic cleavage by plasma kallikrein.

1985 • 26 citations

Enhanced degradation of trypsin-treated low density lipoprotein by fibroblasts from a patient with homozygous familial hypercholesterolemia

1978 • 22 citations

Plasmin-treated low density lipoproteins: polypeptide analyses and metabolism by cultured smooth muscle cells.

1980 • 18 citations

Latent Dyslipoproteinemias and Atherosclerosis

1984 • 15 citations