Distribution and Function of Lymphocyte Surface Antigens

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1991 • 796 citations

Human naive and memory T cells

1988 • 793 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

1990 • 745 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Structure and Function of Leukocyte Integrins

1990 • 620 citations

Transfer of specificity by murine α and β T-cell receptor genes

1986 • 568 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1986 • 437 citations

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes.

1992 • 437 citations

Anti-leu-3/T4 antibodies react with cells of monocyte/macrophage and langerhans lineage

1984 • 426 citations

Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors

1991 • 366 citations

CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

1992 • 342 citations

Monoclonal antibodies identifying a novel T-Cell antigen and Ia antigens of human lymphocytes

1980 • 326 citations

The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes

1985 • 325 citations

Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway

1991 • 325 citations

Anti-Leu-3/T4 antibodies react with cells of monocyte/macrophage and Langerhans lineage.

1983 • 323 citations

The B-cell surface protein CD72/Lyb-2 is the ligand for CDS

1991 • 305 citations

B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas.

1982 • 297 citations

Human Ig superfamily CTLA‐4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA‐4 cytoplasmic domains

1988 • 296 citations

Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen).

1985 • 285 citations

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

1991 • 262 citations

Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.

1987 • 259 citations

Is T-cell memory maintained by crossreactive stimulation?

1990 • 253 citations

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

1982 • 237 citations

The B-cell antigen receptor complex

1991 • 213 citations

B7, a B-cell-restricted antigen that identifies preactivated B cells.

1987 • 211 citations

A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes.

1986 • 191 citations

Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells.

1986 • 165 citations

Overlapping but Nonidentical Binding Sites on CD2 for CD58 and a Second Ligand CD59

1992 • 165 citations

Lectin-dependent and anti-CD3 induced cytotoxicity are preferentially mediated by peripheral blood cytotoxic T lymphocytes expressing Leu-7 antigen.

1986 • 164 citations

A second subunit of CD8 is expressed in human T cells.

1988 • 155 citations

Monoclonal antibodies to the CD5 antigen can provide the necessary second signal for activation of isolated resting T cells by solid-phase-bound OKT3.

1986 • 144 citations

Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti‐CD28 and anti‐CD2 monoclonal antibodies

1988 • 128 citations

Induction of nonspecific cytotoxicity by monoclonal anti-T3 antibodies.

1985 • 126 citations

The roles of CD4 and CD8 in T cell activation.

1991 • 86 citations

IL-4 and IL-2 upregulate the expression of antigen B7, the B cell counterstructure to T cell CD28: an amplification mechanism for T-B cell interactions

1991 • 85 citations

An immunological role for the CD8 β-chain

1992 • 76 citations

CD58 and CD59 molecules exhibit potentializing effects in T cell adhesion and activation.

1992 • 73 citations

Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes.

1988 • 68 citations

The human Lyt-3 molecule requires CD8 for cell surface expression.

1988 • 65 citations

T cell receptor genes do not rearrange or express functional transcripts in natural killer cells of scid mice.

1987 • 59 citations

Targeted cytotoxic cells in human peripheral blood lymphocytes.

1990 • 53 citations

Triggering CD 28 molecules synergize with CD 2 (T11.1 and T11,2)‐mediated T cell activation

1988 • 51 citations

A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation.

1988 • 45 citations

7 Development of Mouse Hematopoietic Lineages

1991 • 22 citations