An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcriptional activators.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

1984 • 976 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1985 • 825 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

The Fos Complex and Fos-Related Antigens Recognize Sequence Elements That Co ntain AP-1 Binding Sites

1988 • 532 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

[The role of protein kinase C in cell surface signal transduction and tumor promotion].

1986 • 508 citations

Trans -Acting Transcriptional Regulation of Human T-Cell Leukemia Virus Type III Long Terminal Repeat

1985 • 500 citations

Pathogenesis of Infection with Human Immunodeficiency Virus

1987 • 496 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 471 citations

Activation of the HIV-1 LTR by T Cell Mitogens and the Trans-Activator Protein of HTLV-I

1987 • 460 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1990 • 330 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus.

1987 • 306 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

1986 • 303 citations

Human immunodeficiency virus long terminal repeat responds to T-cell activation signals.

1987 • 292 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Expression and Characterization of the Trans -Activator of HTLV-III/LAV Virus

1986 • 276 citations

Alternative Mechanisms for Activation of Human Immunodeficiency Virus Enhancer in T Cells

1988 • 265 citations

The NF-kappa B binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity

1989 • 215 citations

Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes.

1985 • 203 citations

Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay

1987 • 176 citations

Phorbol ester enhances human immunodeficiency virus-promoted gene expression and acts on a repeated 10-base-pair functional enhancer element.

1987 • 164 citations

Phorbol ester induces the transcriptional stimulatory activity of the SV40 enhancer

1986 • 146 citations

Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5′ and 3′ flanking homology with other RNA polymerase II transcribed genes.

1983 • 135 citations

Tumor promoter, TPA, enhances replication of HTLV-III/LAV

1986 • 133 citations

Characterization of Long Terminal Repeat Sequences of HTLV-III

1985 • 133 citations

Orientation-Dependent Transcriptional Activator Upstream of a Human U2 snRNA Gene

1985 • 132 citations

The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer

1987 • 129 citations

The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters.

1990 • 123 citations

Oncogenic transformation by vrel requires an amino-terminal activation domain.

1990 • 123 citations

Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID.

1990 • 116 citations

Phorbol ester induces c-sis gene transcription in stem cell line K-562.

1986 • 115 citations

The chronology of AIDS research

1987 • 101 citations

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

1987 • 100 citations

Transactivation of gene expression by nuclear and cytoplasmic rel proteins.

1989 • 100 citations

p59v-rel, the transforming protein of reticuloendotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells

1988 • 71 citations

Alterations in binding characteristics of the human immunodeficiency virus enhancer factor

1988 • 67 citations

Viral rel and cellular rel associate with cellular proteins in transformed and normal cells.

1989 • 51 citations

Orientation-dependent transcriptional activator upstream of a human U2 snRNA gene.

1985 • 49 citations

Oncogenic Transformation by vRel Requires an Amino-Terminal Activation Domain

1990 • 49 citations

Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts.

1989 • 49 citations

Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines.

1987 • 46 citations

Response of individual adenovirus promoters to the products of the E1A gene.

1987 • 44 citations

Interaction of the v-rel protein with an NF-kappa B DNA binding site.

1991 • 33 citations

Transcription of mammalian genes in vitro.

1981 • 18 citations

A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene.

1991 • 16 citations

Phorbol Ester Enhances Human Immunodeficiency Virus-Promoted Gene Expression and Acts on a Repeated 10-Base-Pair Functional Enhancer Element

1987 • 13 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 12 citations

Complex Protein Interactions at the Human Immunodeficiency Virus Type 1 Hiv-1 Direct Repeat Enhancer Structure a Paradigm for Database Analysis of Protein-Nucleic Acid Interactions

1990 • 1 citations