Expression of Multiple Subtypes of Muscarinic Receptors and Cellular Distribution in the Human Heart

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

Muscarinic Receptor Subtypes

1990 • 1,346 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Antagonist binding profiles of five cloned human muscarinic receptor subtypes.

1991 • 605 citations

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

1987 • 442 citations

Molecular Mechanisms Underlying Ionic Remodeling in a Dog Model of Atrial Fibrillation

1999 • 356 citations

Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats.

1994 • 304 citations

A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes

1983 • 298 citations

Muscarinic Receptor Subtypes

1989 • 241 citations

Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells.

1990 • 234 citations

Differential Distribution of Inward Rectifier Potassium Channel Transcripts in Human Atrium Versus Ventricle

1998 • 216 citations

Potential Molecular Basis of Different Physiological Properties of the Transient Outward K ⁺ Current in Rabbit and Human Atrial Myocytes

1999 • 198 citations

Muscarinic receptor differentiation

1988 • 158 citations

Pharmacological characterization of acetylcholine‐stimulated [³⁵S]‐GTPγS binding mediated by human muscarinic m1–m4 receptors: antagonist studies

1993 • 156 citations

Selective Muscarinic Receptor Agonists and Antagonists

1996 • 137 citations

Direct labeling of rat M3-muscarinic receptors by [3H]4DAMP

1989 • 110 citations

Methoctramine, a polymethylene tetraamine, differentiates three subtypes of muscarinic receptor in direct binding studies

1988 • 94 citations

Chapter 12: Muscarinic acetylcholine receptor subtypes: localization and structure/function

1993 • 93 citations

Identification and characterization of multiple subtypes of muscarinic acetylcholine receptors and their physiological functions in canine hearts.

1999 • 76 citations

Embryonic chick heart expresses multiple muscarinic acetylcholine receptor subtypes. Isolation and characterization of a gene encoding a novel m2 muscarinic acetylcholine receptor with high affinity for pirenzepine.

1991 • 73 citations

Molecular and Functional Identification of m ₁ Muscarinic Acetylcholine Receptors in Rat Ventricular Myocytes

1996 • 72 citations

The M5 (m5) receptor subtype: Fact or fiction?

1997 • 70 citations

Muscarinic receptors and drugs in cardiovascular medicine

1995 • 67 citations

Characterization of muscarinic receptor subtypes in human tissues

1988 • 63 citations

Heterogeneous binding of [³H]4‐DAMP to muscarinic cholinergic sites in the rat brain: Evidence from membrane binding and autoradiographic studies

1991 • 56 citations

Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M₃ receptor and a K⁺ current

1999 • 53 citations

A further search for selective antagonists at M₂‐muscarinic receptors

1986 • 53 citations

Choline Modulates Cardiac Membrane Repolarization by Activating an M3 Muscarinic Receptor and its Coupled K+ Channel

1999 • 48 citations

Vascular muscarinic receptors: pharmacological characterization in the bovine coronary artery.

1988 • 45 citations

Structure‐activity relationships of new analogues of arecaidine propargyl ester at muscarinic M₁ and M₂ receptor subtypes

1989 • 44 citations

M<sub>1</sub>, M<sub>3</sub> and M<sub>5</sub> Muscarinic Receptors Stimulate Mitogen-Activated Protein Kinase

1998 • 37 citations

Identification and Molecular Characterization of a m5 Muscarinic Receptor in A2058 Human Melanoma Cells

1996 • 36 citations

A novel M3 muscarinic acetylcholine receptor is expressed in chick atrium and ventricle.

1994 • 34 citations

Does mammalian heart contain only the m2 muscarinic receptor subtype?

1997 • 33 citations

Analysis of muscarinic cholinoceptors mediating phosphoinositide hydrolysis in guinea pig cardiac muscle

1992 • 27 citations

Cardiac M2 receptors consist of two different types, both regulated by GTP

1987 • 27 citations

Vagal Stimulation of the Heartbeat: Muscarinic Receptor Hypothesis

1991 • 26 citations

Muscarinic Receptor Heterogeneity in Neonatal Rat Ventricular Myocytes in Culture

1996 • 22 citations

Characterization of Muscarinic Receptor Subtypes in Canine Left Ventricular Membranes

1992 • 21 citations

Localization and characterization of the subtypes(s) of muscarinic receptor involved in prostacyclin synthesis in rabbit heart.

1996 • 18 citations

Pseudo-Noncompetitive Antagonism of M1, M3, and M5Muscarinic Receptor-Mediated Ca2+Mobilization by Muscarinic Antagonists

1998 • 15 citations

Muscarinic receptor subtypes mediating negative chrono‐ and inotropic responses in isolated, blood‐perfused dog right atria

1990 • 12 citations

Effect of M2 muscarinic receptor antagonist 4-DAMP, on prostaglandin synthesis and mechanical function in the isolated rabbit heart

1989 • 9 citations