Embryonic chick heart expresses multiple muscarinic acetylcholine receptor subtypes. Isolation and characterization of a gene encoding a novel m2 muscarinic acetylcholine receptor with high affinity for pirenzepine.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Current protocols in molecular biology

1988 • 7,584 citations

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization

1982 • 699 citations

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

1988 • 691 citations

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

1987 • 687 citations

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

1989 • 627 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

The mas oncogene encodes an angiotensin receptor

1988 • 390 citations

Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat

1986 • 373 citations

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence

1986 • 344 citations

Clonal analysis of differentiated function in animal cell cultures. I. Possible correlated maintenance of differentiated function and the diploid karyotype.

1966 • 278 citations

Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

1989 • 259 citations

Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells.

1990 • 234 citations

Selective coupling with K+ currents of muscarinic acetylcholine receptor subtypes in NG108-15 cells

1988 • 216 citations

Muscarinic acetylcholine receptors in developing chick heart

1977 • 177 citations

Molecular Biology of Visual Pigments

1987 • 168 citations

Molecular distinction between muscarinic acetylcholine receptor subtypes

1987 • 162 citations

Isolation, sequence, and functional expression of the mouse M1 muscarinic acetylcholine receptor gene.

1988 • 126 citations

Relationships between phosphoinositide and calcium responses to muscarinic agonists in astrocytoma cells.

1984 • 125 citations

In vivo regulation of muscarinic acetylcholine receptor number and function in embryonic chick heart.

1981 • 103 citations

The putative M1 muscarinic receptor does not regulate phosphoinositide hydrolysis. Studies with pirenzepine and McN-A343 in chick heart and astrocytoma cells.

1985 • 92 citations

Cloning and functional analysis of a gene encoding a novel muscarinic acetylcholine receptor expressed in chick heart and brain.

1990 • 80 citations

Differential tissue expression and developmental regulation of guanine nucleotide binding regulatory proteins and their messenger RNAs in rat heart.

1988 • 77 citations

Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development

1987 • 52 citations

A novel subtype of muscarinic receptor identified by homology screening

1987 • 49 citations

Effect of the lipid environment on the differential affinity of purified cerebral and atrial muscarinic acetylcholine receptors for pirenzepine.

1989 • 38 citations

The porcine heart M2 muscarinic receptor: agonist-induced phosphorylation and comparison of properties with the chick heart receptor.

1989 • 33 citations

Muscarinic acetylcholine receptor function in chick heart cells cultured in serum-free medium

1988 • 29 citations

Differences in antagonist affinities at muscarinic receptors in chick and guinea‐pig

1988 • 17 citations

Muscarinic M1-receptors mediate the negative inotropic effect of methacholine in chicken but not in guinea-pig atria

1987 • 6 citations