The Saccharomyces cerevisiae SPT8 gene encodes a very acidic protein that is functionally related to SPT3 and TATA-binding protein.

Basic local alignment search tool

1990 • 87,358 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1991 • 497 citations

Histone Function in Transcription

1990 • 354 citations

Changes in histone gene dosage alter transcription in yeast.

1988 • 275 citations

Vector systems for the expression, analysis and cloning of DNA sequence in S. cerevisiae

1985 • 265 citations

Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions

1989 • 256 citations

SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo

1989 • 239 citations

Molecular mechanisms of transcriptional regulation in yeast

1990 • 224 citations

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.

1992 • 217 citations

The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiae

1984 • 212 citations

A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

1988 • 197 citations

Pig heart calpastatin: identification of repetitive domain structures and anomalous behavior in polyacrylamide gel electrophoresis

1988 • 190 citations

Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning.

1987 • 185 citations

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

1991 • 179 citations

REGULATORY PROTEINS IN YEAST

1987 • 173 citations

Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae.

1991 • 171 citations

Anionic regions in nuclear proteins.

1987 • 167 citations

Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase

1991 • 152 citations

Autoregulation of 2?m circle gene expression provides a model for maintenance of stable plasmid copy levels

1988 • 122 citations

A second form of the beta subunit of signal-transducing G proteins.

1987 • 118 citations

Three Genes Are Required for trans-Activation of Ty Transcription in Yeast

1987 • 102 citations

The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription.

1989 • 101 citations

Biochemical and genetic characterization of a yeast TFIID mutant that alters transcription in vivo and DNA binding in vitro.

1992 • 35 citations

Analysis of the yeastSPT3gene and identification of its product, a positive regulator of Ty trarscription

1986 • 32 citations