Genetic Evidence for a Role for Protein Kinase A in the Maintenance of Sleep and Thalamocortical Oscillations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Two-Process Model of Sleep Regulation

2008 • 3,914 citations

Narcolepsy in orexin Knockout Mice

1999 • 3,014 citations

Function and Regulation of CREB Family Transcription Factors in the Nervous System

2002 • 2,037 citations

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

1996 • 1,253 citations

Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory

1997 • 1,228 citations

Coordinated Interactions between Hippocampal Ripples and Cortical Spindles during Slow-Wave Sleep

1998 • 1,040 citations

Sleep deprivation: Effect on sleep stages and EEG power density in man

1981 • 1,001 citations

Replay and Time Compression of Recurring Spike Sequences in the Hippocampus

1999 • 920 citations

PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity

2003 • 871 citations

The cognitive neuroscience of sleep: neuronal systems, consciousness and learning

2002 • 780 citations

Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep

2008 • 780 citations

Sleep, Learning, and Dreams: Off-line Memory Reprocessing

2001 • 748 citations

Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase

2000 • 646 citations

Aircraft and road traffic noise and children's cognition and health: a cross-national study

2005 • 627 citations

Cognitive Behavioral Therapy for Treatment of Chronic Primary Insomnia

2001 • 607 citations

Memory consolidation during sleep: a neurophysiological perspective

1998 • 560 citations

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

1994 • 542 citations

CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

1995 • 530 citations

Neurobiology of REM and NREM sleep

2007 • 500 citations

Triggering sleep slow waves by transcranial magnetic stimulation

2007 • 462 citations

Sleep in Drosophila is regulated by adult mushroom bodies

2006 • 452 citations

Deficits of Cognitive Executive Functions in Patients With Sleep Apnea Syndrome

1995 • 381 citations

Obstructive Sleep Apnea Syndrome: Pathogenesis of Neuropsychological Deficits

1991 • 378 citations

Gene expression in the brain across the sleep–waking cycle11Published on the World Wide Web on 30 October 2000.

2000 • 363 citations

A Prospective Study of Some Effects of Aircraft Noise on Cognitive Performance in Schoolchildren

2002 • 338 citations

The K-complex: Its slow (<1-Hz) rhythmicity and relation to delta waves

1997 • 329 citations

Dynamics of electroencephalographic sleep spindles and slow wave activity in men: effect of sleep deprivation

1993 • 315 citations

The influence of learning on sleep slow oscillations and associated spindles and ripples in humans and rats

2009 • 305 citations

Sleep-dependent motor memory plasticity in the human brain

2005 • 298 citations

Genetic Determinants of Sleep Regulation in Inbred Mice

1999 • 286 citations

Genetic variation in EEG activity during sleep in inbred mice

1998 • 282 citations

Sleep problems in children with mental handicap

1991 • 258 citations

Elevated Sleep Spindle Density after Learning or after Retrieval in Rats

2006 • 247 citations

Genome-wide association of sleep and circadian phenotypes

2007 • 244 citations

A Comparison of Rates of Residual Insomnia Symptoms Following Pharmacotherapy or Cognitive-Behavioral Therapy for Major Depressive Disorder

2007 • 244 citations

The effects of normal aging on sleep spindle and K-complex production

2002 • 236 citations

Discharge rate and excitability of cortically projecting intralaminar thalamic neurons during waking and sleep states

1982 • 229 citations

A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis

2001 • 224 citations

TMS-Induced Cortical Potentiation during Wakefulness Locally Increases Slow Wave Activity during Sleep

2007 • 220 citations

Sleep and memory: a molecular perspective

2001 • 218 citations

Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.

1995 • 212 citations

Exposure-Effect Relations between Aircraft and Road Traffic Noise Exposure at School and Reading Comprehension

2005 • 203 citations

Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation

2006 • 202 citations

Contrasting patterns in the localization of glutamic acid decarboxylase and Ca2+ /calmodulin protein kinase gene expression in the rat centrat nervous system

1992 • 193 citations

Memory Consolidation in Sleep

2004 • 192 citations

Spectral analysis methods for neurological signals

1998 • 186 citations

Sleep Deprivation by the “Flower Pot” Technique and Spatial Reference Memory

1997 • 168 citations

Sleep Deprivation Impairs Long-Term Potentiation in Rat Hippocampal Slices

2002 • 166 citations

Learning, Memory, and Executive Control in Individuals With Obstructive Sleep Apnea Syndrome

2002 • 160 citations

Topography of EEG Dynamics After Sleep Deprivation in Mice

2000 • 155 citations

Sleep-wake habits and disorders in a series of 100 adult epilepsy patients—A prospective study

2006 • 154 citations

The Role of Sleep in Memory Consolidation and Brain Plasticity: Dream or Reality?

2006 • 137 citations

Modulation of a pacemaker current through Ca2+-induced stimulation of cAMP production

1999 • 134 citations

Sleep Maintenance Insomnia: Strengths and Weaknesses of Current Pharmacologic Therapies

2006 • 131 citations

Genetic Evidence for a Role of CREB in Sustained Cortical Arousal

2003 • 126 citations

Parallel Instabilities of Long-Term Potentiation, Place Cells, and Learning Caused by Decreased Protein Kinase A Activity

2000 • 126 citations

An Automated System for Recording and Analysis of Sleep in Mice

2000 • 115 citations

Adrenergic Signaling Plays a Critical Role in the Maintenance of Waking and in the Regulation of REM Sleep

2004 • 115 citations

Time for the Sleep Community to Take a Critical Look at the Purported Role of Sleep in Memory Processing

2005 • 108 citations

Decreased Sleep Spindles and Spindle Activity in Midlife Women with Fibromyalgia and Pain

2004 • 104 citations

Restraint increases prolactin and REM sleep in C57BL/6J mice but not in BALB/cJ mice

2001 • 100 citations

The Selective Extrasynaptic GABAA Agonist, Gaboxadol, Improves Traditional Hypnotic Efficacy Measures and Enhances Slow Wave Activity in a Model of Transient Insomnia

2007 • 89 citations

Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease

2006 • 85 citations

Imaging Physiologic Dysfunction of Individual Hippocampal Subregions in Humans and Genetically Modified Mice

2000 • 84 citations

Sleep Continuity Measured By Survival Curve Analysis

2006 • 82 citations

Sleep Circuitry and the Hypnotic Mechanism of GABA<SUB>A</SUB> Drugs

2006 • 76 citations

Control of slow oscillations in the thalamocortical neuron: a computer model

1996 • 73 citations

Characteristics of Spindle Activity and Their Use in Evaluation of Hypnotics

1982 • 71 citations

β-Adrenergic receptor activation during distinct patterns of stimulation critically modulates the PKA-dependence of LTP in the mouse hippocampus

2008 • 68 citations

Homeostatic process and sleep spindles in patients with sleep-maintenance insomnia (SMI): effect of partial (21 h) sleep deprivation (PSD)

1998 • 67 citations

Sleep architecture, slow wave activity and sleep spindles in mild sleep disordered breathing

2003 • 63 citations

Mutational Analysis of GNAS1 in Patients with Pseudohypoparathyroidism: Identification of Two Novel Mutations1

2000 • 59 citations

Spindle frequency remains slow in sleep apnea patientsthroughout the night

2003 • 54 citations

Genetic and pharmacological demonstration of a role for cyclic AMP‐dependent protein kinase‐mediated suppression of protein phosphatases in gating the expression of late LTP

2002 • 53 citations

Fully automated sleep deprivation in mice as a tool in sleep research

2007 • 52 citations

Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer’s disease

2001 • 49 citations

Sensory Deprivation Unmasks a PKA-Dependent Synaptic Plasticity Mechanism that Operates in Parallel with CaMKII

2008 • 49 citations

Chronic exposure of rats to noise: Relationship between long-term memory deficits and slow wave sleep disturbances

2006 • 47 citations

Sleep Spindles: Pharmacological Effects in Humans

1982 • 47 citations

Children's cognition and aircraft noise exposure at home--the West London Schools Study.

2005 • 41 citations

Activity Level-Dependent Synapse-Specific AMPA Receptor Trafficking Regulates Transmission Kinetics

2009 • 40 citations

Postsynaptic Muscarinic M1 Receptors Activate Prefrontal Cortical EEG of C57BL/6J Mouse

2002 • 31 citations

Sleep-Wake Patterns in Children With Intrauterine Growth Retardation

2002 • 28 citations

Changes in the levels of cyclic nucleotides in rat brain during the sleep-wakefulness cycle

1981 • 21 citations

Rolipram, an Antidepressant That Increases the Availability of cAMP, Transiently Enhances Wakefulness in Rats

1998 • 20 citations

The Effects of Diazepam on Sleep Spindles: A Qualitative and Quantitative Analysis

2001 • 17 citations

Sleep fragmentation in mentally retarded people decreases with increasing daylength in spring

2002 • 12 citations

Protein phosphorylation in rat mammary acini and in cytosol preparations in vitro Phosphorylation of acetyl-CoA carboxylase is unaffected by cyclic AMP

1987 • 10 citations