Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer’s disease

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

The NINCDS‐ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease

1988 • 611 citations

PROTEIN KINASES IN THE BRAIN

1985 • 559 citations

Protein Phosphorylation and Neuronal Function

1985 • 525 citations

Protein phosphorylation in the brain

1983 • 428 citations

CREB: A mediator of long-term memory from mollusks to mammals

1994 • 371 citations

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type

1999 • 202 citations

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome

1999 • 184 citations

Protein Kinases in the Brain

1985 • 134 citations

Neuronal phosphoproteins

1987 • 132 citations

Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome

1997 • 102 citations

Activation of Presynaptic cAMP-Dependent Protein Kinase Is Required for Induction of Cerebellar Long-Term Potentiation

1999 • 99 citations

Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multiinfarct dementia

1984 • 65 citations

Differential expression of ARPP-16 and ARPP-19, two highly related cAMP- regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions

1990 • 64 citations

Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue

1994 • 61 citations

Adenylyl cyclase activity in Alzheimer's disease brain: stimulatory and inhibitory signal transduction pathways are differently affected

1994 • 56 citations

Impaired cyclic AMP production in the hippocampus of a Down syndrome murine model

1996 • 53 citations

Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.

1990 • 53 citations

Regulation by cAMP and vasoactive intestinal peptide of phosphorylation of specific proteins in striatal cells in culture.

1988 • 50 citations

Ca2+/CaM-sensitive adenylyl cyclase activity is decreased in the Alzheimer's brain: Possible relation to type I adenylyl cyclase

1997 • 40 citations

Reduced immunoreactivity of adenylyl cyclase in dementia of the Alzheimer type

1996 • 39 citations

Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem tissues

1991 • 38 citations

Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease

1993 • 33 citations

Reduced cAMP-signal transduction in postmortem hippocampus of demented old people.

1989 • 21 citations