Short- and longer-term regulation of very-low-density lipoprotein secretion by insulin, dexamethasone and lipogenic substrates in cultured hepatocytes. A biphasic effect of insulin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Reappraisal of the role of insulin in hypertriglyceridemia

1974 • 480 citations

Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol

1984 • 393 citations

The use of a non‐ionic detergent (Triton WR 1339) to determine rates of triglyceride entry into the circulation of the rat under different physiological conditions

1967 • 292 citations

The glucose paradox. Is glucose a substrate for liver metabolism?

1984 • 273 citations

Effects of Insulin and Glucose on Very Low Density Lipoprotein Triglyceride Secretion by Cultured Rat Hepatocytes

1982 • 215 citations

Intrahepatic assembly of very low density lipoproteins. Effect of fatty acids on triacylglycerol and apolipoprotein synthesis.

1982 • 179 citations

Role of insulin in lipoprotein secretion by cultured rat hepatocytes.

1983 • 168 citations

Short-term Hormonal Control of Hepatic Lipogenesis

1980 • 156 citations

Diurnal Patterns of Triglycerides, Free Fatty Acids, Blood Sugar, and Insulin during Carbohydrate-Induction in Man and Their Modification by Nocturnal Suppression of Lipolysis

1973 • 145 citations

In vitro reversal of the fasting state of liver metabolism in the rat. Reevaluation of the roles of insulin and glucose.

1981 • 141 citations

Increased free cholesterol in plasma low and very low density lipoproteins in non-insulin-dependent diabetes mellitus: its role in the inhibition of cholesteryl ester transfer.

1984 • 135 citations

Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes

1986 • 127 citations

Glucocorticoid-induced Insulin Resistance

1982 • 125 citations

Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig.

1985 • 110 citations

Surface binding, internalization and degradation by cultured human fibroblasts of low density lipoproteins isolated from Type 1 (insulin-dependent) diabetic patients: Changes with metabolic control

1982 • 108 citations

Synthesis of fatty acids in the perfused mouse liver

1974 • 100 citations

Human noninsulin-dependent diabetes: identification of a defect in plasma cholesterol transport normalized in vivo by insulin and in vitro by selective immunoadsorption of apolipoprotein E.

1982 • 91 citations

Hyperlipidaemia of diabetes

1986 • 85 citations

The effects of glucocorticoids on insulin-stimulated lipogenesis in primary cultures of rat hepatocytes

1983 • 84 citations

Effects of insulin on lipoprotein secretion in rat hepatocyte cultures. The role of the insulin receptor.

1986 • 72 citations

Contributions of fatty acid and sterol synthesis to triglyceride and cholesterol secretion by the perfused rat liver in genetic hyperlipemia and obesity.

1985 • 67 citations

Dietary carbohydrate induces lipogenesis and very-low-density lipoprotein synthesis

1984 • 66 citations

Effects of hormones and pyruvate on the rates of secretion of very-low-density lipoprotein triacylglycerol and cholesterol by rat hepatocytes

1985 • 60 citations

Relationship between activity of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase and secretion of very-low-density-lipoprotein cholesterol by the isolated perfused liver and in the intact rat

1979 • 50 citations

Dietary Control of Circadian Variations in Serum Insulin, Glucagon and Hepatic Cyclic AMP

1980 • 41 citations

The relationship between the rate of hepatic sterol synthesis and the incorporation of [3H]water.

1983 • 35 citations

Control of hepatic triacylglycerol synthesis. Diurnal variations in hepatic phosphatidate phosphohydrolase activity and in the concentrations of circulating insulin and corticosterone in rats

1979 • 33 citations

Regulation of hepatic very-low-density lipoprotein secretion in rats fed on a diet high in unsaturated fat

1987 • 29 citations

Evidence for a direct effect of bacitracin on cell-mediated insulin degradation in isolated hepatocytes

1982 • 24 citations

Lipoprotein lipase hydrolysis of trioleoylglycerol in a phospholipid interface. Effect of cholesteryl oleate on catalysis.

1985 • 24 citations

Changes in the sensitivity of lipogenesis in rat hepatocytes to hormones and precursors over the diurnal cycle and during longer-term starvation of donor animals.

1984 • 24 citations

Hepatic lipoprotein biosynthesis

1986 • 14 citations