Essential role for Max in early embryonic growth and development

c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism

1999 • 1,650 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation

1996 • 787 citations

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

1994 • 617 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

Regulation of zygotic gene activation in the mouse

1993 • 569 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice.

1993 • 536 citations

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

1993 • 392 citations

The molecular role of Myc in growth and transformation: recent discoveries lead to new insights

1998 • 381 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

1992 • 365 citations

Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.

1992 • 314 citations

Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse

1993 • 206 citations

Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth

1998 • 197 citations

A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung.

1992 • 189 citations

Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo.

1989 • 172 citations

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

1994 • 159 citations

Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation

1998 • 135 citations

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.

1994 • 125 citations

Expression and Activity of L-Myc in Normal Mouse Development

1996 • 119 citations

Repression by the Mad(Mxi1)-Sin3 complex

1998 • 110 citations

Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro.

1995 • 98 citations

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

1995 • 94 citations

max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors.

1992 • 92 citations

The Nerve Growth Factor-Responsive PC12 Cell Line Does Not Express the Myc Dimerization Partner Max

1995 • 85 citations

Translocation of a store of maternal cytoplasmic c-myc protein into nuclei during early development.

1989 • 77 citations

Zebra fish myc family and max genes: differential expression and oncogenic activity throughout vertebrate evolution.

1993 • 76 citations

WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras.

1995 • 70 citations

Two MAD tails: what the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network

1999 • 68 citations

Function of the c-Myc Antagonist Mad1 during a Molecular Switch from Proliferation to Differentiation

1997 • 66 citations

Use of transgenic mice to study myc family gene function in normal mammalian development and in cancer.

1994 • 66 citations

Repression of Myc-Ras cotransformation by Mad is mediated by multiple protein-protein interactions.

1995 • 61 citations

The nuclear envelope: Its breakdown and fate in mammalian oogonia and oocytes

1972 • 51 citations

Expression ofmyc-family,myc-interacting, andmyc-target genes during preimplantation mouse development

1997 • 39 citations

GROWTH AND ITS CONTROL IN EARLY MAMMALIAN DEVELOPMENT

1981 • 30 citations

Selective and Rapid Nuclear Translocation of a c-Myc-Containing Complex after Fertilization of Xenopus laevis Eggs

1995 • 27 citations

Zebra Fish myc Family and max Genes: Differential Expression and Oncogenic Activity throughout Vertebrate Evolution

1993 • 17 citations

Translocation of a Store of Maternal Cytoplasmic c-myc Protein into Nuclei during Early Development

1989 • 11 citations