Augmented Mitogenic Responsiveness to Epidermal Growth Factor in Murine Fibroblasts That Overexpress pp60^c-src

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.

1973 • 1,126 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

1986 • 406 citations

Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).

1979 • 378 citations

Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.

1986 • 329 citations

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.

1980 • 298 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Protein kinase C phosphorylates pp60src at a novel site

1985 • 243 citations

The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor.

1985 • 207 citations

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells.

1985 • 171 citations

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1984 • 163 citations

Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells.

1984 • 161 citations

The development of insulin receptors and responses in the differentiating nonfusing muscle cell line BC3H-1.

1984 • 105 citations

pp60c-src kinase is in chick and human embryonic tissues

1984 • 103 citations

Potentiation of growth factor activity by exogenous c-myc expression.

1986 • 99 citations

S phase synchrony in monolayer CHO cultures

1976 • 80 citations

Oncogene-mediated multistep transformation of C3H10T1/2 cells.

1987 • 37 citations

pp60^c‐src is a substrate for phosphorylation when cells are stimulated to enter cycle

1984 • 30 citations

Novel serine phosphorylation of pp60c-src in intact cells after tumor promoter treatment.

1986 • 29 citations

Reduced tyrosine kinase specific activity is associated with hypophosphorylation of pp60c-src in cells infected with avian erythroblastosis virus.

1987 • 9 citations

The role of EGF receptor transmodulation in embryonal carcinoma-derived growth factor-induced mitogenesis.

1986 • 9 citations