Identification of a site on herpes simplex virus type 1 glycoprotein D that is essential for infectivity

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Prediction of protein conformation

1974 • 3,327 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

1985 • 702 citations

A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cells

1988 • 514 citations

Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion

1988 • 468 citations

Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells

1984 • 384 citations

Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity

1979 • 364 citations

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

1987 • 333 citations

Molecular Genetics of Herpes Simplex Virus II. Mapping of the Major Viral Glycoproteins and of the Genetic Loci Specifying the Social Behavior of Infected Cells

1979 • 303 citations

Herpes Simplex Virus Type-1 Glycoprotein D Gene: Nucleotide Sequence and Expression inEscherichia coli

1982 • 285 citations

Neutralizing monoclonal antibodies specific for herpes simplex virus glycoprotein D inhibit virus penetration

1987 • 250 citations

Anti-glycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surface.

1987 • 245 citations

Type-common and type-specific monoclonal antibody to herpes simplex virus type 1

1980 • 239 citations

Differential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein.

1988 • 210 citations

A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1

1981 • 208 citations

Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus

1988 • 204 citations

Neutralizing antibodies specific for glycoprotein H of herpes simplex virus permit viral attachment to cells but prevent penetration

1989 • 201 citations

Excretion of Non-infectious Virus Particles Lacking Glycoprotein H by a Temperature-sensitive Mutant of Herpes Simplex Virus Type 1: Evidence that gH Is Essential for Virion Infectivity

1988 • 185 citations

Herpes simplex viruses lacking glycoprotein D are unable to inhibit virus penetration: quantitative evidence for virus-specific cell surface receptors

1988 • 181 citations

Localization of discontinuous epitopes of herpes simplex virus glycoprotein D: use of a nondenaturing ("native" gel) system of polyacrylamide gel electrophoresis coupled with Western blotting

1986 • 169 citations

Linker-insertion nonsense and restriction-site deletion mutations of the gB glycoprotein gene of herpes simplex virus type 1

1987 • 168 citations

Fine mapping of antigenic site II of herpes simplex virus glycoprotein D

1989 • 167 citations

Herpes simplex virus glycoprotein D mediates interference with herpes simplex virus infection

1989 • 165 citations

Localization of epitopes of herpes simplex virus type 1 glycoprotein D

1985 • 164 citations

Molecular Biology of Pseudorabies Virus

1985 • 141 citations

DNA sequence of the gene for pseudorabies virus gp50, a glycoprotein without N-linked glycosylation

1986 • 139 citations

Glycoprotein cytoplasmic domain sequences required for rescue of a vesicular stomatitis virus glycoprotein mutant

1989 • 124 citations

Functional regions and structural features of the gB glycoprotein of herpes simplex virus type 1

1988 • 121 citations

Potent neutralizing activity associated with anti-glycoprotein D specificity among monoclonal antibodies selected for binding to herpes simplex virions

1985 • 120 citations

Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration

1988 • 117 citations

Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cells

1988 • 117 citations

Synthetic glycoprotein D-related peptides protect mice against herpes simplex virus challenge

1985 • 114 citations

Mutants of the Rous sarcoma virus envelope glycoprotein that lack the transmembrane anchor and cytoplasmic domains: analysis of intracellular transport and assembly into virions

1987 • 113 citations

Differences in attachment between herpes simplex type 1 and type 2 viruses to neurons and glial cells

1980 • 97 citations

Physical mapping of the mutation in an antigenic variant of herpes simplex virus type 1 by use of an immunoreactive plaque assay

1983 • 97 citations

Mutations affecting conformation or sequence of neutralizing epitopes identified by reactivity of viable plaques segregate from syn and ts domains of HSV-1(F) gB gene

1984 • 93 citations

DNA sequence of the Herpes simplex virus type 2 glycoprotein D gene

1983 • 87 citations

Evidence for Herpes Simplex Virus Type-selective Receptors on Cellular Plasma Membranes

1979 • 84 citations

Herpes Simplex Virus Glycoprotein D: Human Monoclonal Antibody Produced by Bone Marrow Cell Line

1983 • 74 citations

Antigenic analysis of a major neutralization site of herpes simplex virus glycoprotein D, using deletion mutants and monoclonal antibody-resistant mutants

1988 • 66 citations

Comparative structural analysis of glycoprotein gD of herpes simplex virus types 1 and 2

1980 • 63 citations

Fine structure analysis of type-specific and type-common antigenic sites of herpes simplex virus glycoprotein D

1984 • 57 citations

Alterations in Glycoprotein gB Specified by Mutants and Their Partial Revertants in Herpes Simplex Virus Type 1 and Relationship to Other Mutant Phenotypes

1980 • 56 citations

Antigenic and functional analysis of a neutralization site of HSV-1 glycoprotein D

1990 • 54 citations

The contribution of cysteine residues to antigenicity and extent of processing of herpes simplex virus type 1 glycoprotein D

1988 • 52 citations

Influence of peptide acylation, liposome incorporation, and synthetic immunomodulators on the immunogenicity of a 1-23 peptide of glycoprotein D of herpes simplex virus: implications for subunit vaccines

1990 • 51 citations

Reduced yield of infectious pseudorabies virus and herpes simplex virus from cell lines producing viral glycoprotein gp50

1988 • 49 citations

Expression of herpes simplex virus type 1 major DNA-binding protein, ICP8, in transformed cell lines: complementation of deletion mutants and inhibition of wild-type virus

1987 • 37 citations

Construction and characterization of CV-1P cell lines which constitutively express the simian virus 40 agnoprotein: alteration of plaquing phenotype of viral agnogene mutants

1986 • 34 citations

Shortened cytoplasmic domain affects intracellular transport but not nuclear localization of a viral glycoprotein.

1990 • 30 citations

Regulation of glycoprotein D synthesis: does alpha 4, the major regulatory protein of herpes simplex virus 1, regulate late genes both positively and negatively?

1988 • 28 citations

Cloning of Herpes simplex virus type 2 DNA fragments in a plasmid vector

1980 • 24 citations

The carboxy-terminal 41 amino acids of herpes simplex virus type 1 glycoprotein B are not essential for production of infectious virus particles

1988 • 22 citations

Electronic fingerprinting of RNA

1988 • 21 citations

Mutants defective in herpes simplex virus type 2 ICP4: isolation and preliminary characterization

1987 • 21 citations

Effects of altered cytoplasmic domains on transport of the vesicular stomatitis virus glycoprotein are transferable to other proteins.

1988 • 20 citations

The cytoplasmic domain of herpes simplex virus type 1 glycoprotein C is required for membrane anchoring

1988 • 15 citations

Replacement of the pseudorabies virus glycoprotein gIII gene with its postulated homolog, the glycoprotein gC gene of herpes simplex virus type 1

1989 • 13 citations

Effects of Altered Cytoplasmic Domains on Transport of the Vesicular Stomatitis Virus Glycoprotein Are Transferable to Other Proteins

1988 • 7 citations

Deleted Work

1955 • 0 citations