Properties of NMDA receptor channels in neurons acutely isolated from epileptic (kindled) rats

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

Numerical Recipes--The Art of Scientific Computing.

1988 • 5,058 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

Numerical Recipes in C-The Art of Scientific Computing.

1989 • 1,645 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Giant synaptic potentials in immature rat CA3 hippocampal neurones.

1989 • 1,302 citations

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1992 • 1,077 citations

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 • 979 citations

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

1992 • 962 citations

Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

1987 • 934 citations

Data transformations for improved display and fitting of single-channel dwell time histograms

1987 • 828 citations

Potassium channels as multi-ion single-file pores.

1978 • 816 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Fast events in single‐channel currents activated by acetylcholine and its analogues at the frog muscle end‐plate.

1985 • 768 citations

Activity-Dependent Decrease in NMDA Receptor Responses During Development of the Visual Cortex

1992 • 731 citations

Rates of diffusional exchange between small cells and a measuring patch pipette

1988 • 712 citations

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

1990 • 570 citations

Voltage dependence of NMDA-activated macroscopic conductances predicted by single-channel kinetics

1990 • 568 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Selective modulation of NMDA responses by reduction and oxidation

1989 • 459 citations

Control by Asparagine Residues of Calcium Permeability and Magnesium Blockade in the NMDA Receptor

1992 • 437 citations

Tonic Activation of NMDA Receptors by Ambient Glutamate Enhances Excitability of Neurons

1989 • 434 citations

An enzymatic mechanism for calcium current inactivation in dialysed Helix neurones.

1986 • 409 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling

1987 • 401 citations

Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

1993 • 394 citations

Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus

1991 • 370 citations

A quantitative description of NMDA receptor-channel kinetic behavior

1990 • 323 citations

GABA _A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors

1988 • 303 citations

Cloning, expression and modulation of a mouse NMDA receptor subunit

1992 • 291 citations

Identification by mutagenesis of a Mg2+ -block site of the NMDA receptor channel

1992 • 264 citations

Modulation of calcium channels by norepinephrine in internally dialyzed avian sensory neurons.

1985 • 242 citations

Regulation of N‐methyl‐D‐aspartate receptors revealed by intracellular dialysis of murine neurones in culture.

1989 • 225 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

Long-term potentiation : a debate of current issues

1991 • 216 citations

TheN-methyl-D-aspartate antagonists aminophosphonovalerate and car☐ypiperazinephosphonate retard the development and expression of kindled seizures

1990 • 196 citations

Role of the receptors in the development and maintenance of hippocampal kindling in rats

1988 • 190 citations

cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor

1983 • 187 citations

Activation of N‐methyl‐D‐aspartate receptors by L‐glutamate in cells dissociated from adult rat hippocampus.

1992 • 182 citations

The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists

1983 • 180 citations

N-methyl-D-aspartate receptor plasticity in kindling: quantitative and qualitative alterations in the N-methyl-D-aspartate receptor-channel complex.

1989 • 143 citations

Isolated NMDA receptor-mediated synaptic responses express both LTP and LTD

1992 • 133 citations

Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices

1991 • 130 citations

Currents through single glutamate receptor channels in outside‐out patches from rat cerebellar granule cells.

1991 • 129 citations

Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique

1988 • 125 citations

Epileptiform discharges evoked in hippocampal brain slices from epileptic patients

1989 • 120 citations

Reduced sensitivity of the component of synaptic transmission to magnesium in hippocampal slices from immature rats

1990 • 103 citations

Glutamate activation of a single NMDA receptorchannel produces a cluster of channel openings

1991 • 99 citations

The effect of agonist concentration, membrane voltage and calcium on n-methyl-d-aspartate receptor desensitization

1990 • 98 citations

Excitatory Amino Acid Receptors

1980 • 96 citations

Biochemical and immunohistochemical correlates of kindling-induced epilepsy: role of calcium binding protein

1983 • 95 citations

Biochemical evidence for enhanced sensitivity to N-methyl-d-aspartate in the hippocampal formation of kindled rats

1989 • 95 citations

Stochastic properties of ion channel openings and bursts in a membrane patch that contains two channels: evidence concerning the number of channels present when a record containing only single openings is observed

1990 • 92 citations

On the multiple‐conductance single channels activated by excitatory amino acids in large cerebellar neurones of the rat.

1989 • 88 citations

Endogenous intracellular calcium buffering and the activation/inactivation of HVA calcium currents in rat dentate gyrus granule cells.

1991 • 86 citations

N-methyl-d-aspartate receptor autoradiography in rat brain after angular bundle kindling

1989 • 82 citations

On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons

1988 • 72 citations

Entorhinal kindling permanently enhances Ca2+-dependentL-glutamate release in regio inferior of rat hippocampus

1990 • 69 citations

Differential activation of glutamate receptors by spontaneously released transmitter in slices of neocortex

1990 • 69 citations

Whole‐cell current noise produced by excitatory and inhibitory amino acids in large cerebellar neurones of the rat.

1989 • 45 citations

Whole-cell voltage-clamp recordings in granule cells acutely isolated from hippocampal slices of adult or aged rats

1989 • 42 citations

Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-d-aspartate

1991 • 26 citations

Single channel properties of the N-methyl-D-aspartate receptor channel using NMDA and NMDA agonists: on-cell recordings

1990 • 22 citations

Effects of amygdaloid kindling on NMDA receptor function and regulation

1989 • 19 citations

Cumulative frequency curves in population analysis

1990 • 9 citations

Developmental changes in acetylcholine receptor channel structure and function as a model for synaptic plasticity

1992 • 8 citations

Sites For Antagonism On The N-Methyl-D-Aspartate Receptor Channel Complex

1991 • 6 citations