Dysgenesis of cephalic neural crest derivatives in Pax7−/− mutant mice

The Neural Crest

1999 • 2,996 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

MyoD or Myf-5 is required for the formation of skeletal muscle

1993 • 1,663 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

Homology of the eyeless Gene of Drosophila to the Small eye Gene in Mice and Aniridia in Humans

1994 • 1,075 citations

The MyoD family and myogenesis: Redundancy, networks, and thresholds

1993 • 1,062 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

The triple origin of skull in higher vertebrates: a study in quail-chick chimeras

1993 • 981 citations

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

1992 • 973 citations

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

1991 • 897 citations

The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues

1983 • 852 citations

Function of the retinoic acid receptors (RARs) during development: (I) Craniofacial and skeletal abnormalities in RAR double mutants

1994 • 755 citations

Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death

1992 • 700 citations

Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene

1992 • 692 citations

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

1991 • 664 citations

Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo

1991 • 635 citations

Roles of Pax-genes in developing and adult brain as suggested by expression patterns

1994 • 582 citations

Two myogenic lineages within the developing somite

1992 • 570 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila

1986 • 497 citations

Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells

1994 • 495 citations

Regulation of Pax-3 expression in the dermomyotome and its role in muscle development

1994 • 491 citations

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

1990 • 479 citations

An exonic mutation in the HuP2 paired domain gene causes Waardenburg's syndrome

1992 • 470 citations

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

1992 • 470 citations

Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis

1991 • 443 citations

The control of avian cephalic neural crest cytodifferentiation

1978 • 417 citations

Pax in development

1992 • 402 citations

Rescue of the En-1 Mutant Phenotype by Replacement of En-1 with En-2

1995 • 402 citations

The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system

1990 • 383 citations

Mapping of the early neural primordium in quail-chick chimeras

1985 • 378 citations

Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification

1994 • 372 citations

The contribution of both forebrain and midbrain crest cells to the mesenchyme in the frontonasal mass of mouse embryos

1994 • 357 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 326 citations

A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells

1993 • 309 citations

Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development

1988 • 304 citations

Analysis of the developmental effects of a lethal mutation in the house mouse

1954 • 290 citations

The molecular basis of the undulated/Pax-1 mutation

1991 • 273 citations

Characterization and Developmental Expression of Pax9, a Paired-Box-Containing Gene Related to Pax1

1995 • 263 citations

Teratocarcinomas and Embryonic Stem Cells: A Practical Approach

1988 • 263 citations

Participation of neural crest-derived cells in the genesis of the skull in birds

1978 • 262 citations

Transgenes as probes for active chromosomal domains in mouse development

1988 • 251 citations

Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed.

1995 • 228 citations

Mutations in the PAX3 gene causing Waardenburg syndrome type 1 and type 2

1993 • 223 citations

Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis.

1987 • 213 citations

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9

1993 • 212 citations

Conservation of the paired domain in metazoans and its structure in three isolated human genes.

1989 • 210 citations

The Splotch mutation interferes with muscle development in the limbs

1993 • 205 citations

Pax: Gene regulators in the developing nervous system

1993 • 195 citations

PAX genes

1994 • 190 citations

Analysis of cranial neural crest cell migration and early fates in postimplantation rat chimaeras

1986 • 132 citations

Mechanisms of neural crest cell migration

1993 • 118 citations

Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column

1994 • 116 citations

Molecular basis of splotch and Waardenburg Pax-3 mutations.

1994 • 114 citations

A frameshift mutation in the HuP2 paired domain of the probable human homolog of murine Pax-3 is responsible for Waardenburg syndrome type 1 in an Indonesian family

1992 • 93 citations

The gooseberry-zipper region of Drosophila : five genes encode different spatially restricted transcripts in the embryo

1987 • 87 citations

A Transgenic Neuroanatomical Marker Identifies Cranial Neural Crest Deficiencies Associated with the Pax3 Mutant Splotch

1995 • 76 citations

Pax genes in development

1994 • 73 citations

Defective Ensheathment of Motoric Nerves in the Splotch Mutant Mouse

1990 • 65 citations

A new Pax gene, Pax-9, maps to mouse Chromosome 12

1993 • 51 citations

Spinal ganglia reduction in the splotch‐delayed mouse neural tube defect mutant

1989 • 49 citations

Pax in our time

1991 • 19 citations

Mouse mutations and human disorders are paired

1992 • 16 citations