Analysis of the F8 gene in individuals with high plasma factor VIII: C levels and associated venous thrombosis.

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

1996 • 3,124 citations

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

1993 • 1,997 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis

1995 • 1,117 citations

The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells

1993 • 583 citations

The Risk of Recurrent Venous Thromboembolism in Patients with an Arg⁵⁰⁶→Gln Mutation in the Gene for Factor V (Factor V Leiden)

1997 • 380 citations

High Prevalence of Elevated Factor VIII Levels in Patients Referred for Thrombophilia Screening: Role of Increased Synthesis and Relationship to the Acute Phase Reaction

1997 • 229 citations

Activation of Blood Coagulation after Abrupt or Stepwise Withdrawal of Oral Anticoagulants - A Prospective Study

1994 • 107 citations

Genotypic Variation in the Promoter Region of the Protein C Gene Is Associated With Plasma Protein C Levels and Thrombotic Risk

1995 • 104 citations

cis-Acting Elements and Transcription Factors Involved in the Promoter Activity of the Human Factor VIII Gene

1995 • 76 citations

The influence of factor VIII on measurement of activated protein C resistance

1996 • 73 citations

Role of the Liver-Enriched Transcription Factor Hepatocyte Nuclear Factor 1 in Transcriptional Regulation of the Factor VIII Gene

1996 • 41 citations

Immunologic studies of factor VIII coagulant activity (VIII:C) 1. Assays based on a haemophilic and an acquired antibody to VIII:C

1981 • 39 citations

Thrombo-Embolism in Patients with Abnormally Short Activated Partial Thromboplastin Time

1977 • 25 citations

Acute-phase behavior of factor VIII procoagulant and other acute-phase reactants in rabbits

1989 • 23 citations

Plasma factor VII levels are influenced by a polymorphism in the promoter region of the FVII gene

1996 • 23 citations

Polymorphic variation in the human protein C (PROC) gene promoter can influence transcriptional efficiency in vitro

1995 • 17 citations