Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Plaque assay techniques for murine leukemia viruses

1970 • 1,271 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

1986 • 828 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

A detailed model of reverse transcription and tests of crucial aspects

1979 • 621 citations

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.

1981 • 601 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase

1981 • 439 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.

1984 • 407 citations

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

1985 • 342 citations

Structure of mouse metallothionein-I gene and its mRNA

1981 • 301 citations

SV40 gene expression is modulated by the cooperative binding of T antigen to DNA

1981 • 300 citations

Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs

1982 • 283 citations

Gene Expression in Mice After High Efficiency Retroviral-Mediated Gene Transfer

1985 • 281 citations

Nucleotide sequence of the genome of a murine sarcoma virus

1981 • 267 citations

The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells

1982 • 265 citations

Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells

1984 • 258 citations

Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses

1973 • 245 citations

Construction of a helper cell line for avian reticuloendotheliosis virus cloning vectors.

1983 • 214 citations

Isolation and characterization of the mouse metallothionein-I gene.

1980 • 210 citations

Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus

1981 • 203 citations

The terminal nucleotides of retrovirus DNA are required for integration but not virus production

1983 • 193 citations

Relationship of retrovirus polyprotein cleavages to virion maturation studied with temperature-sensitive murine leukemia virus mutants

1978 • 192 citations

In vitro synthesis of a 9 kbp terminally redundant DNA carrying the infectivity of moloney murine leukemia virus

1979 • 186 citations

Expression of a Retrovirus Encoding Human HPRT in Mice

1984 • 182 citations

Factors involved in production of helper virus-free retrovirus vectors

1986 • 181 citations

Varying the position of a retrovirus packaging sequence results in the encapsidation of both unspliced and spliced RNAs

1985 • 165 citations

The primer tRNA for Moloney murine leukemia virus DNA synthesis. Nucleotide sequence and aminoacylation of tRNAPro.

1979 • 157 citations

Genetically stable reassortment of markers during mixed infection with avian tumor viruses

1971 • 138 citations

Generation of Helper-Free Amphotropic Retroviruses That Transduce a Dominant-Acting, Methotrexate-Resistant Dihydrofolate Reductase Gene

1985 • 125 citations

Analysis of the env gene of a molecularly cloned and biologically active Moloney mink cell focus-forming proviral DNA

1982 • 125 citations

Amphotropic retrovirus vector system for human cell gene transfer.

1984 • 117 citations

A viral interference test for mouse leukemia viruses

1967 • 109 citations

Construction of a Helper Cell Line for Avian Reticuloendotheliosis Virus Cloning Vectors

1983 • 99 citations

Deletion mutants of Moloney murine leukemia virus which lack glycosylated gag protein are replication competent

1983 • 95 citations

Mutations in the gag gene of Moloney murine leukemia virus: effects on production of virions and reverse transcriptase

1984 • 89 citations

Genetic Recombination among Temperature-sensitive Mutants of Rous Sarcoma Virus

1974 • 87 citations

Characterization of a Rous sarcoma virus mutant defective in packaging its own genomic RNA: biological properties of mutant TK15 and mutant-induced transformants

1984 • 79 citations

Elements in the long terminal repeat of murine retroviruses enhance stable transformation by thymidine Idnase gene

1983 • 66 citations

An Association Between Globin Messenger RNA and 60S RNA Derived from Friend Leukemia Virus

1974 • 55 citations

Amphotropic Retrovirus Vector System for Human Cell Gene Transfer

1984 • 55 citations

Isolation of recombinant DNA clones carrying complete integrated proviruses of Moloney murine leukemia virus

1981 • 53 citations

Chemical and Enzymatic Synthesis of Gene Fragments A Laboratory Manual

1984 • 47 citations

Evidence for genetic recombination between endogenous and exogenous mouse RNA type C viruses

1974 • 38 citations

Genetic studies of temperature-sensitive mutants of Moloney-murine leukemia virus

1973 • 38 citations

The Recombination and Integration of DNAs Introduced into Mouse L Cells

1984 • 26 citations

Genetic Recombination in Rous Sarcoma Virus: the Genesis of Recombinants and Lack of Evidence for Linkage between pol, env and src Genes in Three Factor Crosses

1979 • 24 citations

Temperature-Sensitive Mutants of Murine Leukemia Virus IV. Further Physiological Characterization and Evidence for Genetic Recombination

1974 • 19 citations

Immunoselection and characterization of moloney murine leukemia virus-infected cell lines deficient in surface gag antigen expression

1981 • 12 citations