Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

1985 • 922 citations

Selective Protection against Conidia by Mononuclear and against Mycelia by Polymorphonuclear Phagocytes in Resistance to Aspergillus

1982 • 624 citations

Inhibition of Granulocyte Adherence by Ethanol, Prednisone, and Aspirin, Measured with an Assay System

1974 • 496 citations

Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis

1989 • 495 citations

GRANULOCYTE COLONY-STIMULATING FACTOR AND NEUTROPHIL RECOVERY AFTER HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS BONE MARROW TRANSPLANTATION

1989 • 440 citations

Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge

1988 • 428 citations

Granulocyte Colony-Stimulating Factor Enhances the Phagocytic and Bactericidal Activity of Normal and Defective Human Neutrophils

1991 • 323 citations

FUNGAL INFECTIONS IN LIVER TRANSPLANT RECIPIENTS

1985 • 280 citations

Immune interferon enhances functional properties of human granulocytes: role of Fc receptors and effect of lymphotoxin, tumor necrosis factor, and granulocyte-macrophage colony-stimulating factor.

1987 • 254 citations

In Vivo Bronchoalveolar Macrophage Defense Against Rhizopus oryzae and Aspergillus fumigatus

1984 • 254 citations

A Rapid Colorimetric Assay of Fungal Viability with the Tetrazolium Salt MTT

1985 • 222 citations

Enhancement of oxidative response and damage caused by human neutrophils to Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon

1993 • 209 citations

Damage to hyphal forms of fungi by human leukocytes in vitro. A possible host defense mechanism in aspergillosis and mucormycosis.

1978 • 209 citations

Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide

1987 • 207 citations

Therapeutic concentrations of glucocorticoids suppress the antimicrobial activity of human macrophages without impairing their responsiveness to gamma interferon.

1985 • 206 citations

Opportunistic Infections in Endogenous Cushing's Syndrome

1984 • 195 citations

Modulation of human polymorphonuclear leukocyte IgG Fc receptors and Fc receptor-mediated functions by IFN-gamma and glucocorticoids.

1988 • 182 citations

Interaction of leukocyte chemotactic factors with the cell surface. I. Chemotactic factor-induced changes in human granulocyte surface charge.

1975 • 148 citations

Cellular immunity after intravenous administration of methylprednisolone.

1974 • 147 citations

Alterations in Cyclic AMP Metabolism in Human Bronchial Asthma. III. LEUKOCYTE AND LYMPHOCYTE RESPONSES TO STEROIDS

1973 • 133 citations

Patterns of Infection in Patients with Aplastic Anemia and the Emergence of Aspergillus As a Major Cause of Death

1992 • 128 citations

Normal and Deficient Neutrophils Can Cooperate to Damage Aspergillus fumigatus Hyphae

1990 • 127 citations

Mechanisms of Attachment of Neutrophils to Candida albicans Pseudohyphae in the Absence of Serum, and of Subsequent Damage to Pseudohyphae by Microbicidal Processes of Neutrophils In Vitro

1978 • 126 citations

Opposing effects of glucocorticoids on interferon-gamma-induced murine macrophage Fc receptor and Ia antigen expression.

1985 • 123 citations

Effects of in vivo dexamethasone administration on in vitro bovine polymorphonuclear leukocyte function

1981 • 122 citations

In Vivo Interferon- Therapy Augments the In Vitro Ability of Chronic Granulomatous Disease Neutrophils to Damage Aspergillus Hyphae

1991 • 121 citations

Impairment of neutrophil chemotactic and bactericidal function in children infected with human immunodeficiency virus type 1 and partial reversal after in vitro exposure to granulocyte-macrophage colony-stimulating factor

1990 • 116 citations

Female hormones reduce neutrophil responsiveness in vitro

1984 • 113 citations

Interferon-gamma activates human neutrophil oxygen metabolism and exocytosis.

1988 • 106 citations

Disparate effects of interferon-gamma and tumor necrosis factor-alpha on early neutrophil respiratory burst and fungicidal responses to Candida albicans hyphae in vitro.

1991 • 98 citations

A corticosteroid binding protein and endogenous ligand in C. albicans indicating a possible steroid-receptor system

1981 • 92 citations

IFN-gamma and LPS overcome glucocorticoid inhibition of priming for superoxide release in human monocytes. Evidence that secretion of IL-1 and tumor necrosis factor-alpha is not essential for monocyte priming.

1989 • 82 citations

Inhibition of Monocyte-Mediated Damage to Fungal Hyphae by Steroid Hormones

1983 • 66 citations

Activation of Murine Polymorphonuclear Neutrophils for Fungicidal Activity by Recombinant Gamma Interferon

1987 • 66 citations

Protective effect of human granulocyte colony‐stimulating factor (hG‐CSF) on Cryptococcus and Aspergillus infections in normal and immunosuppressed mice

1991 • 66 citations

Studies on the pathogenesis of experimental pulmonary aspergillosis.

1967 • 61 citations

The Intracellular Fate of Histoplasma capsulatum in Human Macrophages Is Unaffected by Recombinant Human Interferon-

1990 • 60 citations

Clinical experience with recombinant human granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor.

1989 • 58 citations

Stress Hormones Modulate Neutrophil and Lymphocyte Activity in vitro

1987 • 52 citations

The mechanism of action of the antiinflammatory agents dexamethasone and Auranofin in human polymorphonuclear leukocytes

1983 • 50 citations

Invasive pulmonary aspergillosis in patients with neoplastic diseases.

1990 • 48 citations

Hydrocortisone inhibits the respiratory burst oxidase from human neutrophils in whole-cell and cell-free systems

1990 • 45 citations

Invasive Aspergillosis Complicating Cushing's Syndrome

1981 • 45 citations

Evidence for the involvement of distinct signal transduction pathways in the regulation of constitutive and interferon gamma-dependent gene expression of NADPH oxidase components (gp91-phox, p47-phox, and p22- phox) and high-affinity receptor for IgG (Fc gamma R-I) in human polymorphonuclear leukocytes

1992 • 42 citations

Distribution of a Corticosteroid-binding Protein in Candida and Other Fungal Genera

1983 • 42 citations

Unopsonized Candida albicans Hyphae Stimulate a Neutrophil Respiratory Burst and a Cytosolic Calcium Flux Without Membrane Depolarization

1987 • 41 citations

Gamma Interferon Enhances the Killing of Staphylococcus aureus by Human Neutrophils

1988 • 40 citations

Quantitative Determination of Dexamethasone in Human Plasma by Stable Isotope Dilution Mass Spectrometry

1984 • 39 citations

Prednisolone inhibits phagocytosis by polymorphonuclear leucocytes via steroid receptor mediated events

1983 • 37 citations

Comparison of methylprednisolone (1 g i.v.) with prednisolone (1 g orally) in rheumatoid arthritis: a pharmacokinetic and clinical study.

1988 • 36 citations

Stimulation of oxidative metabolism in murine polymorphonuclear leukocytes by unopsonized fungal cells: evidence for a mannose-specific mechanism.

1981 • 28 citations

Inhibition of neutrophil Fc receptor function by cotricosteroids.

1978 • 27 citations

Induction of Signal Transduction in Human Neutrophils by Candida albicans Hyphae: The Role of Pertussis Toxin-Sensitive Guanosine Triphosphate-Binding Proteins

1988 • 16 citations

Chemotactic factor production by rat polymorphonuclear leukocytes: Stimulation with opsonized zymosan particles and inhibition by dexamethasone

1984 • 14 citations

Hydrocortisone sodium succinate reversibly inhibits human neutrophil oxidative activity at clinically relevant concentrations

1983 • 9 citations

Effect of dexamethasone on polypeptides synthesised in polymorphonuclear leucocytes

1985 • 8 citations

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