Sequences involved in the regulated expression of the human interferon-beta1 gene in recombinant SV40 DNA vectors replicating in monkey cells.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

[16] Plasmids of Escherichia coli as cloning vectors

1979 • 655 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

The structure of one of the eight or more distinct chromosomal genes for human interferon-α

1980 • 486 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.

1980 • 341 citations

Mechanisms and applications of DNA-mediated gene transfer in mammalian cells — a review

1981 • 188 citations

Definition of a novel promoter for the major adenovirus-associated virus mRNA

1980 • 187 citations

Eukaryotic viral vectors

1982 • 177 citations

Analysis of interferon mRNA in human fibroblast cells induced to produce interferon.

1981 • 147 citations

Expression of the chromosomal mouse βmaj-globin gene cloned in SV40

1979 • 135 citations

Structure of a chromosomal gene for human interferon β

1981 • 133 citations

Human fibroblast interferon gene lacks introns

1981 • 112 citations

Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells.

1982 • 85 citations

Regulation in vivo of a cloned mammalian gene: cadmium induces the transcription of a mouse metallothionein gene in SV40 vectors.

1982 • 82 citations

Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.

1982 • 76 citations

Controlled transcription of a human α-interferon gene introduced into mouse L cells

1982 • 72 citations

Inducer-responsive expression of the cloned human interferonβ₁gene introduced into cultured mouse cells

1982 • 70 citations

Nucleotide sequence of the chromosomal gene for human fibroblast (β1) interferon and of the flanking regions

1981 • 67 citations

The structure of a thirty-six kilobase region of the human chromosome including the fibroblast interferon gene IFN-β

1981 • 66 citations

Inducibility of human β-interferon gene in mouse L-cell clones

1982 • 66 citations

SIMIAN VIRUS 40 AS A EUKARYOTIC CLONING VEHICLE

1981 • 63 citations

Sequence heterogeneity at the 5' termini of late simian virus 40 19S and 16S mRNAs.

1979 • 59 citations

Synthesis of Human Interferon β₁ in Escherichia coliInfected by a Lambda Phage Recombinant containing a Human Genomic Fragment

1981 • 42 citations

Specific in vitro initiation of transcription of simian virus 40 early and late genes occurs at the various cap nucleotides including cytidine.

1981 • 39 citations

The interferon renaissance: molecular aspects of induction and action

1981 • 34 citations

Expression of human β-interferon cDNA under the control of a thymidine kinase promoter from herpes simplex virus

1982 • 29 citations

Induction of human beta-interferon synthesis with poly(rI . rC) in mouse cells transfected with cloned cDNA plasmids.

1982 • 21 citations

Monkey interferon: Activity on human cells and chromatographic properties

1979 • 7 citations